gms | German Medical Science

47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

04.09. - 07.09.2019, Dresden

Experimentelle und Translationale Rheumatologie

Meeting Abstract (ET.01)

Amphiregulin attenuates lupus nephritis via suppression of pro-inflammatory T-cell functions in an animal model of SLE

Melderis S, Warkotsch M, Hagenstein J, Herrnstadt GR, Tiegs G, Steinmetz OM
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Meeting Abstract (ET.02)

Vergleichende Analyse von Biologika-Effekten auf IL-17A- und TNF-induzierte Zytokinsekretion synovialer Fibroblasten von Patienten mit rheumatoider Arthritis oder Psoriasisarthritis

Frommer K, Rehart S, Müller-Ladner U, Neumann E
[Volltext]
Meeting Abstract (ET.03)

Culture-expanded human iNKT cells modulate regulatory and effector B cells of SSc patients

Asteriti E, Duerr-Stoerzer S, Keppeler H, Schmid H, Secker KA, Pecher AC, Henes J, Klein R, Schneidawind C, Schneidawind D
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Meeting Abstract (ET.04)

CXCL17 is inducible by INF-γ and inhibits angiogenesis in rheumatoid arthritis

Kernder AL, Mucke J, Tang-Chieu L, Lowin T, Claßen T, Sander O, Bleck E, Heier C, Pongratz G, Schneider M, Vordenbäumen S
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Meeting Abstract (ET.05)

BCP and CPPD crystalopathies exhibit distinct effects on the chondrocyte phenotype

Meyer F, Pap T, Kornak U, Bollmann M, Bertrand J
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Meeting Abstract (ET.06)

The ghrelin system is regulated by nutrient availability and pro-inflammatory cytokines in rheumatoid arthritis synovial fibroblasts

Lowin T, Lesmann H, Oebels B, Schneider M, Pongratz G
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Meeting Abstract (ET.07)

CD38 is up-regulated on plasmablasts and memory T-Lymphocytes and in SLE and may represent a promising future therapeutic target

Ostendorf L, Enghard P, Richter U, Hiepe F, Alexander T
[Volltext]
Meeting Abstract (ET.08)

Resetting the immune system with immunoablation followed by autologous stem cell transplantation is associated with long-term remissions in SLE

Alexander T, Biesen R, Ostendorf L, Burmester GR, Grützkau A, Thiel A, Radbruch A, Arnold R, Hiepe F
[Volltext]
Meeting Abstract (ET.09)

Enhanced IL-7 receptor signaling in SLE promotes T-helper cell proliferation through upregulation of microRNA-182 and downregulation of FOXO1

Alexander T, Haftmann C, Riedel R, Humrich J, Burmester GR, Radbruch A, Hiepe F, Mashreghi MF
[Volltext]
Meeting Abstract (ET.10)

Modulation von synovialen Fibroblasten durch Syk-Inhibitoren bei rheumatoider Arthritis

Diller M, Lallah Missimana P, Hasseli R, Rehart S, Müller-Ladner U, Neumann E
[Volltext]
Meeting Abstract (ET.11)

Die Interaktion von Endothelzellen und synovialen Fibroblasten wird durch Aktivin A und Follistatin bei Patienten mit rheumatoider Arthritis modifiziert

Aykara I, Diller M, Rehart S, Müller-Ladner U, Neumann E
[Volltext]
Meeting Abstract (ET.12)

STING-associated vasculopathy in mice requires adaptive immunity but not type I interferon or cGAS

Luksch H, Gerbaulet A, Stinson A, Platt DJ, Qian W, Kalugotla G, Miner CA, Bennion BG, Miner J, Rösen-Wolff A
[Volltext]
Meeting Abstract (ET.13)

Knorpel-Synovialis-Cokultur: Humanes ex vivo-Modell der Knorpeldegeneration

Mucke J, Warzynski V, Bleck E, Pauly T, Claßen T, Schneider M, Vordenbäumen S
[Volltext]
Meeting Abstract (ET.14)

Decreased C5aR1 autoantibodies correlate with higher relapse rates in ANCA-associated vasculitis

Klapa S, Müller A, Heidecke H, Koch A, Kerstein A, Karsten C, Junker J, Kaehler W, Schinke S, Huber-Lang M, Riemekasten G, Lamprecht P
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Meeting Abstract (ET.15)

The dopaminergic pathway – a potential new way to target B cells in rheumatic diseases

Wieber K, Baraliakos X, Braun J, Capellino S
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Meeting Abstract (ET.16)

Receptor expression of angiotensin type 1 and 2 are decreased and correlate with serological titers of NT-proBNP and the FVC/DLCO ratio in patients with systemic sclerosis and pulmonary arterial hypertension

Klapa S, Pitann S, Marschner G, Riepe S, Koch A, Müller A, Heidecke H, Lamprecht P, Riemekasten G
[Volltext]
Meeting Abstract (ET.17)

Hyperactivation of TLR-signaling in a family with monogenic systemic lupus erythematosus

Kind B, Lara-Villacanas E, Wolf C, Bernbeck B, Siepermann KJ, Niehues T, Lee-Kirsch MA
[Volltext]
Meeting Abstract (ET.18)

Autoantibodies targeting CXCR3 and CXCR4 affect the expression of their cognate receptors in lung tissue of the ApoE knockout mouse model

Brachaczek L, Johanson L, Marschner G, Heidecke H, Aherrahrou Z, Müller A, Riemekasten G
[Volltext]
Meeting Abstract (ET.20)

Interaktionen zwischen synovialen Fibroblasten von Psoriasis-Arthritis-Patienten und Tenozyten durch im synovio-enthesialen Komplex gebildete Zytokine

Dechant F, Frommer K, Millar NL, McInnes I, Rehart S, Müller-Ladner U, Neumann E
[Volltext]
Meeting Abstract (ET.21)

Induzierte pluripotente Stammzellen (hiPSC) mit MEFV-Mutationen zeigen reduzierte antiinflammatorische Eigenschaften

Kessel C, Kessel K, Ludwig N, Weinhage T, Föll D, Wittkowski H
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Meeting Abstract (ET.22)

Differential pattern of autoantibodies targeting G protein-coupled receptors in systemic lupus erythematosus

Luo J, Yue X, Heidecke H, Müller A, Yu X, Riemekasten G
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Meeting Abstract (ET.24)

Abatacept modulates CD80 and CD86 expression in human B cells and ACPA specific memory in RA patients

Lorenzetti R, Janowska I, Smulski CR, Frede N, Henneberger N, Walter L, Schleyer T, Hüppe J, Staniek J, Salzer U, Venhoff AC, Troilo A, Voll R, Venhoff N, Thiel J, Rizzi M
[Volltext]
Meeting Abstract (ET.25)

Janus kinase inhibitors decrease pro-inflammatory as well as immunosuppressive functions of lymphocyte-stimulated synovial fibroblasts

Yao N, Kvacskay P, Tretter T, Souto-Carneiro M, de Albuquerque Carvalho R, Lorenz HM, Tykocinski LO
[Volltext]
Meeting Abstract (ET.26)

IL-34 in the pathogenesis of human rheumatoid and lupus arthritis

Weinmann-Menke J, Meineck M, Cavagna L, Brochhausen C, Weinmann A, Moeckel T, Schwarting A, Kelley V
[Volltext]
Meeting Abstract (ET.27)

The 3D human-based in vitro arthritic joint model

Damerau A, Lang A, Pfeiffenberger M, Buttgereit F, Gaber T
[Volltext]
Meeting Abstract (ET.28)

Integrin α11β1 deficiency affects joint destructions in arthritic hTNFtg mice

Rauwolf KK, Deichsel A, Beckmann D, Hansen U, Kronenberg D, Gullberg D, Pap T, Korb-Pap A
[Volltext]
Meeting Abstract (ET.29)

Caffeine impacts inflammatory markers and apoptosis rates in cultured human SLE B-cells in comparison to normal controls

Siekierka-Harreis M, Schroedter M, Brinks R, Chehab G, Richter J, Opgenoorth B, Schneider M, Pongratz G
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Meeting Abstract (ET.30)

Prostaglandin receptor EP4 expression by Th17 cells: a new marker of disease activity in ankylosing spondylitis

Meyer A, Klasen C, Waqué I, Wittekind P, Nabhani S, Kofler D
[Volltext]
Meeting Abstract (ET.31)

Identifizierung und Charakterisierung einer neuen genetischen Ursache einer Typ 1-Interferonopathie

Lucas N, Mirtschink P, Wolf C, Ping X, Liu D, Dalgard CL, Boehm M, Lee-Kirsch MA
[Volltext]
Meeting Abstract (ET.33)

Liver X Receptor activation protects from mechanically induced osteoarthritis in mice

Schmidt T, Behler-Janbeck F, Rüther W, Niemeier A
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Meeting Abstract (ET.34)

Influence of dietary fibre and short-chain fatty acids on the pathogenesis of systemic lupus erythematosus (SLE)

Eichhorst A, Schäfer AL, Voll R, Chevalier N
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Meeting Abstract (ET.35)

The cold shock Y-box protein-1 (YB-1) promotes survival of T cells and is deregulated in Systemic Lupus Erythematosus (SLE)

Meltendorf S, Fu H, Pierau M, Gieseler-Halbach S, Handschuh J, Lindquist J, Mertens P, Ambach A, Thomas U, Lingel H, Finzel S, Voll R, Brunner-Weinzierl M
[Volltext]
Meeting Abstract (ET.36)

Cellular biomarkers in SLE to monitor immune cell- and cell signalling-dynamics

Baumgart S, Bertolo M, Urbicht M, Burns T, Biesen R, Rose T, Enghard P, Schulz A, Mei H, Grützkau A
[Volltext]
Meeting Abstract (ET.37)

Lowered anti-beta1 adrenergic receptor antibody concentrations may have prognostic significance in acute coronary syndrome

Ernst D, Westerberg J, Jablonka A, Sogkas G, Ahrenstorf G, Schmidt RE, Heidecke H, Wallentin L, Riemekasten G, Witte T
[Volltext]
Meeting Abstract (ET.38)

Anti-beta-adrenoceptor autoantibodies are elevated in systemic sclerosis

Dreyer TK, Comdühr S, Pitann S, Kerstein A, Marschner G, Heidecke H, Müller A, Riemekasten G
[Volltext]