gms | German Medical Science

26th Annual Meeting of the German Retina Society

German Retina Society

27.09.2013, Hamburg

Article

Send article

Treatment of subretinal hemorrhage with subretinal Injection of recombinant tissue plasminogen activator

Meeting Abstract

Search Medline for

  • Evangelos Chatzizisis - Wuppertal, Germany

Retinologische Gesellschaft. 26. Jahrestagung der Retinologischen Gesellschaft. Hamburg, 27.-27.09.2013. Düsseldorf: German Medical Science GMS Publishing House; 2013. Doc13rg30

doi: 10.3205/13rg30, urn:nbn:de:0183-13rg307

Published: August 20, 2013

© 2013 Chatzizisis.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

The subretinal Injection of recombinant tissue Plasminogen Activator (rtPA) in combination with a Vitrectomy and Gas Tamponade is the primary therapy option in many cases for the treatment of a subretinal hemorrhage.

The target our analysis was the evaluation (visual visual acquity,lesion size, fluorescein angiography, ocular coherence tomography) of the therapeutic response in Patients with subretinal hemorrhage. 20 eyes of 20 patients with submacular hemorrhage due to exudative AMD were included in the study. The hemorrhage lesion size was at least 2 diameter papillae, existing of subfoveal hemorrhages.

RtPA was applied using a 23Gauge ppVitrectomy (30 μgr) followed by a Gas Tamponade (Sulphur Hexafluoride, SF6). Postoperatively was performed an anti-VEGF therapy according to the PRONTO criteria. The anatomical and functional results and postoperative complications were evaluated 4 weeks, 12 weeks and 4 months after the fokal treatment.