Artikel
Treatment of subretinal hemorrhage with subretinal Injection of recombinant tissue plasminogen activator
Suche in Medline nach
Autoren
-
Evangelos Chatzizisis
- Wuppertal, Germany
| Veröffentlicht: | 20. August 2013 |
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Gliederung
Text
The subretinal Injection of recombinant tissue Plasminogen Activator (rtPA) in combination with a Vitrectomy and Gas Tamponade is the primary therapy option in many cases for the treatment of a subretinal hemorrhage.
The target our analysis was the evaluation (visual visual acquity,lesion size, fluorescein angiography, ocular coherence tomography) of the therapeutic response in Patients with subretinal hemorrhage. 20 eyes of 20 patients with submacular hemorrhage due to exudative AMD were included in the study. The hemorrhage lesion size was at least 2 diameter papillae, existing of subfoveal hemorrhages.
RtPA was applied using a 23Gauge ppVitrectomy (30 μgr) followed by a Gas Tamponade (Sulphur Hexafluoride, SF6). Postoperatively was performed an anti-VEGF therapy according to the PRONTO criteria. The anatomical and functional results and postoperative complications were evaluated 4 weeks, 12 weeks and 4 months after the fokal treatment.
