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64th Annual Meeting of the German Society of Neurosurgery (DGNC)

German Society of Neurosurgery (DGNC)

26 - 29 May 2013, Düsseldorf

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Association of aneurysms and variation of the A1 segment

Meeting Abstract

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  • Carolin Gramsch - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Andrej Krasny - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Felix Nensa - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Sophia Göricke - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Oliver Müller - Klinik für Neurochirurgie, Universitätsklinikum Essen
  • Ulrich Sure - Klinik für Neurochirurgie, Universitätsklinikum Essen
  • Isabel Wanke - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Selma Sirin - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Michael Forsting - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen
  • Marc Schlamann - Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen

Deutsche Gesellschaft für Neurochirurgie. 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Düsseldorf, 26.-29.05.2013. Düsseldorf: German Medical Science GMS Publishing House; 2013. DocP 060

doi: 10.3205/13dgnc477, urn:nbn:de:0183-13dgnc4775

Published: May 21, 2013

© 2013 Gramsch et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective: Previous studies have described a correlation between variants of the circle of Willis and pathological findings such as cerebrovascular diseases. Moreover, anatomic variations of the anterior cerebral artery (ACA) seem to correspond to the prevalence of aneurysms in anterior communicating artery (ACoA). The aim of this study is to assess the prevalence of aneurysms in patients with anatomical/morphological variations of the circle of Willis.

Method: We retrospectively analyzed 223 patients who underwent cerebral angiography between January 2002 and December 2010 and had cerebral aneurysm of the ACoA. Diagnostic imaging was reviewed and statistically evaluated to detect circle of Willis anomalies, aneurysm size, and rupture. Two hundred and four patients with unrelated diagnosis served as control group.

Results: Variations of the A1 segment were significantly more frequent in the aneurysm group than in the control group. The mean aneurysm size in patients with grades I and III hypoplasia or aplasia was 6.58 mm whereas that in patients with grade II hypoplasia was 7.76 mm. In addition, aneurysms were significantly more often detected via the contralateral internal carotid artery (ICA) than via the ipsilateral or both ACI.

Conclusions: It can be assumed that variations in the A1 segment of the ACAs are correlated with a higher prevalence of ACoA aneurysms than in patients with a symmetric circle of Willis.