Artikel
Association of aneurysms and variation of the A1 segment
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Veröffentlicht: | 21. Mai 2013 |
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Gliederung
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Objective: Previous studies have described a correlation between variants of the circle of Willis and pathological findings such as cerebrovascular diseases. Moreover, anatomic variations of the anterior cerebral artery (ACA) seem to correspond to the prevalence of aneurysms in anterior communicating artery (ACoA). The aim of this study is to assess the prevalence of aneurysms in patients with anatomical/morphological variations of the circle of Willis.
Method: We retrospectively analyzed 223 patients who underwent cerebral angiography between January 2002 and December 2010 and had cerebral aneurysm of the ACoA. Diagnostic imaging was reviewed and statistically evaluated to detect circle of Willis anomalies, aneurysm size, and rupture. Two hundred and four patients with unrelated diagnosis served as control group.
Results: Variations of the A1 segment were significantly more frequent in the aneurysm group than in the control group. The mean aneurysm size in patients with grades I and III hypoplasia or aplasia was 6.58 mm whereas that in patients with grade II hypoplasia was 7.76 mm. In addition, aneurysms were significantly more often detected via the contralateral internal carotid artery (ICA) than via the ipsilateral or both ACI.
Conclusions: It can be assumed that variations in the A1 segment of the ACAs are correlated with a higher prevalence of ACoA aneurysms than in patients with a symmetric circle of Willis.