gms | German Medical Science

24th Annual Meeting of the German Retina Society

German Retina Society

17.06. - 18.06.2011, Aachen

Anterior chamber aqueous flare as a predictor for proliferative vitreoretinopathy in patients with rhegmatogenous retinal detachment

Meeting Abstract

  • Sascha Fauser - Universitäts-Augenklinik Köln
  • S. Schröder - Universitäts-Augenklinik Köln
  • P.S. Müther - Universitäts-Augenklinik Köln
  • A. Caramoy - Universitäts-Augenklinik Köln
  • M. Diestelhorst - Universitäts-Augenklinik Köln
  • B. Kirchhof - Universitäts-Augenklinik Köln

German Retina Society. 24th Annual Conference of the German Retina Society. Aachen, 17.-18.06.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11rg14

doi: 10.3205/11rg14, urn:nbn:de:0183-11rg146

This is the translated version of the article.
The original version can be found at:

Published: June 15, 2011

© 2011 Fauser et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Purpose: To investigate preoperative aqueous flare as a predictive factor for proliferative vitreoretinopathy (PVR) re-detachment in patients with rhegmatogenous retinal detachment (RD).

Methods: Preoperatively, the aqueous flare of 116 consecutive patients with RD was measured quantitatively with a laser flare meter (LFCM) (Kowa FM-500). Seventy four healthy partner eyes and 41 eyes of healthy age-matched patients served as controls. At least six months after surgery, patients were re-evaluated, whether surgery was performed again due to PVR re-detachment.

Results: RD eyes that developed PVR re-detachment later on (n=12) had higher flare values than eyes with uncomplicated RD (n=104) (median 27.63 photon counts/ms (pc/ms) vs. 8.83 pc/ms; p<0.0001). No eye with PVR re-detachment had a flare value below 10.8 pc/ms. In eyes with flare values exceeding 15 pc/ms, the odds of PVR re-detachment development increases 16-fold.

Conclusion: Our study shows that the breakdown of the blood-ocular barrier as determined by aqueous flare is a major risk factor for PVR re-detachment. The LFM is a fast tool that allows predicting the PVR re-detachment risk preoperatively. It provides the surgeon with an estimate to choose those patients that could benefit from intravitreal drugs to prevent PVR.