gms | German Medical Science

57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

11. bis 14.05.2006, Essen

The International Neuroendoscopic Biopsy Study (INEBS)

Die internationale neuroendoskopische Biopsie-Studie (INEBS)

Meeting Abstract

  • corresponding author T. Riegel - Klinik für Neurochirurgie Universitätsklinikum Gießen und Marburg, Standort Marburg
  • S. Constantini - Dana Children’s Hospital Tel Aviv, Israel
  • S. Sgouros - Alder Hay Children’s Hospital Birmingham, UK
  • R. Abbott - New York University Medical Center, US
  • D. Hellwig - Klinik für Neurochirurgie Universitätsklinikum Gießen und Marburg, Standort Marburg

Deutsche Gesellschaft für Neurochirurgie. Japanische Gesellschaft für Neurochirurgie. 57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie. Essen, 11.-14.05.2006. Düsseldorf, Köln: German Medical Science; 2006. DocFR.12.05

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2006/06dgnc082.shtml

Veröffentlicht: 8. Mai 2006

© 2006 Riegel et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective: Although neuroendoscopic biopsies (NEB) are routinely performed, the safety and validity of NEB has been studied only for a small number of patients in single centre reports. The aim of this study is to collect data on large numbers of NEB patients retrospectively at several international centres known to perform neuroendoscopic procedures on a regular basis.

Methods: Retrospective data collection from 13 centres routinely performing NEB over a period of 5 years. The essential patient data focused on all biopsy attempts. Feedback from the neuropathologist on the study form was essential.

Results: We received 292 patient data forms from13 medical centres in 9 counties. Patients’ age ranged from 0.1 to 78.7 years (median 20.4). Tumour location was pineal (34%), thalamic (18%), intraventricular (21%), tectal (12%), hypothalamic (55) and other locations (10%). Tumour size was <10mm (13%), 10-20mm (36%), and 20mm (50%). In addition to the NEB, 59 had endoscopic third ventriculostomy (ETV) and 14% septum pellucidotomy. There was one intraoperative death reported, due to massive haemorrhage. 80% had a mild bleeding during the procedure, 14% moderate, and 6% severe. Infection occurred in 3%, and other complications, mostly reversible, in 11%. Tumour types ranged across the spectrum, including astrocytoma (low-grade-32%, high-grade-13%), germinoma (11%), PNET (11%), non-neoplastic (5%), and other tumour types (18%). 105 had non-conclusive pathology

Conclusions: This is the largest series looking on the safety and validity of NEB. NEB had a relatively low, and mostly reversible, complication rate of fewer than 13%. Neuroendoscopic biopsy provided meaningful pathological data for 90% of the patients.