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23rd Annual Meeting of the German Retina Society

German Retina Society

24.09. - 25.09.2010, Freiburg

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Vitreomacular interface and posterior vitreomacular adhesion in exsudative age-related macular degeneration (AMD): A Spectralis-OCT-Study

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  • Mathias Maier - Technical University Munich, University Hospital rechts der Isar, Eye Clinic
  • S. Pfrommer - Technical University Munich, University Hospital rechts der Isar, Eye Clinic
  • S. Burzer - Technical University Munich, University Hospital rechts der Isar, Eye Clinic
  • N. Feucht - Technical University Munich, University Hospital rechts der Isar, Eye Clinic
  • C. Winkler von Mohrenfels - Technical University Munich, University Hospital rechts der Isar, Eye Clinic
  • C.P. Lohmann - Technical University Munich, University Hospital rechts der Isar, Eye Clinic

German Retina Society. 23rd Annual Conference of the German Retina Society. Freiburg i. Br., 24.-25.09.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10rg68

doi: 10.3205/10rg68, urn:nbn:de:0183-10rg688

This is the English version of the article.
The German version can be found at: http://www.egms.de/de/meetings/rg2010/10rg68.shtml

Published: September 21, 2010

© 2010 Maier et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Purpose: To evaluate posterior vitreomacular adhesion as a risk factor for choroidal neovascularization (CNV) in age-related macular degeneration (AMD) the vitreoretinal interface was examined using Spectralis-OCT (Heidelberg engineering).

Methods: In a retrospective observational case series 375 consecutive eyes of 375 patients (age 51–90 years) were examined with Spectralis Optical Coherence Tomography (Heidelberg engineering) and fluorescein angiography (FA). Vitreomacular adhesion was defined when the posterior hyaloid line was attached to inner retinal surface as seen in OCT. In 202 patients with exsudative AMD the incidence of posterior vitreomacular adhesion was compared to 173 control patients ( 72 with non-exsudative AMD and 101 without retinal alterations).

Results: We found posterior vitreomacular adhesion in 151 patients (40.3%). In the control group 53 patients (30.6%) showed vitreomacular adhesions compared to 98 patients (48.5%) with exsudative AMD. The difference was statistically significant (p<0,001). The location of vitreomacular adhesion was observed over the area of the CNV in 88.8% of the eyes with exsudative AMD.

Conclusions: Spectralis OCT allows a detailed examination of the vitreomacular interface. The frequency of posterior vitreomacular adhesion is significantly increased in eyes with CNV in AMD. Chronic vitreomacular traction may be a risk factor for the development of exudative AMD.