gms | German Medical Science

22nd Annual Meeting of the German Retina Society

German Retina Society

26.06. - 27.06.2009, Berlin

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6 Cases of Late Manifestation in Retinoblastoma

Meeting Abstract

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  • Gregor Willerding - Charité University Eye Clinic of Berlin, Campus Benjamin Franklin
  • M. Doblhofer - Charité University Eye Clinic of Berlin, Campus Benjamin Franklin
  • M. H. Foerster - Charité University Eye Clinic of Berlin, Campus Benjamin Franklin

German Retina Society. 22nd Annual Meeting of the German Retina Society. Berlin, 26.-27.06.2009. Düsseldorf: German Medical Science GMS Publishing House; 2009. DocRG2009-54

doi: 10.3205/09rg55, urn:nbn:de:0183-09rg558

This is the English version of the article.
The German version can be found at: http://www.egms.de/de/meetings/rg2009/09rg55.shtml

Published: June 29, 2009

© 2009 Willerding et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Background: Retinoblastoma is usually diagnosed in the first two years of life. Later manifestion may be associated with atypical findings and delay in diagnosis.

Method: A single-institutional retrospective case series is presented.

Results: Mean age at diagnosis was 6.7 years (median 5.9 years, range 4.6–11.2 years). Mean time from the onset of first symptoms was 4 months. Presenting signs were ineffective treatment of amblyopia, strabism, visual deterioration and pain. One case was received eye-preserving treatment and four patients underwent enucleation which was a secondary enucleation in one case.

Conclusion: Late Manifestation in Retinoblastoma may present atypically and lead to delayed diagnosis. Enucleation may be advisable in the majority of cases.