gms | German Medical Science

83rd Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

16.05. - 20.05.2012, Mainz

A preliminary study on the influence of obstructive sleep apnea upon parasympathetic system function

Meeting Abstract

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  • corresponding author Min Yin - the First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China
  • Lei Cheng - the First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China
  • R Tabata - Shiga University of Medical Science, Shiga, Japan
  • S Miyazaki - Shiga University of Medical Science, Shiga, Japan

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Mainz, 16.-20.05.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12hnod707

doi: 10.3205/12hnod707, urn:nbn:de:0183-12hnod7075

Published: April 4, 2012

© 2012 Yin et al.
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Outline

Text

The auto never system plays a key role in mediating the cardiovascular changes during obstructive sleep apnea (OSA), while the discussion on parasympathetic nerve system (PNS) activity during sleep apnea were still not enough. The presented study investigated the correlation between cumulative PNS activity and OSA among 76 patients with OSA, by coarse graining spectral analysis of heart rate variability. The results showed cumulative PNS function and PNS peaks were lowly but significantly correlated with OSA severity (r = –0.071, p<0.005 and r = –0.267, p<0.05 respectively), and linear regression equation could be established. Further more, significant correlation was also observed in juvenile and adult groups, and in moderate and severe groups, but not in elder and mild groups. The results indicated that PNS activity might serve as a useful index to evaluate OSA too, combined with other invasive examinations.