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83rd Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

16.05. - 20.05.2012, Mainz

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Endoscopic surgery as treatment modality for olfactory neuroblastoma

Meeting Abstract

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  • corresponding author Qi Wang - Beijing Tongren Hospital, Capital Medical University, Beijing, P.R. China
  • Hongsheng Jia - Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China
  • Xin Ni - Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China
  • Zhigang Huang - Beijing Tongren Hospital, Capital Medical University, Beijing, P.R. China
  • Jugao Fang - Beijing Tongren Hospital, Capital Medical University, Beijing, P.R. China

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Mainz, 16.-20.05.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12hnod132

doi: 10.3205/12hnod132, urn:nbn:de:0183-12hnod1323

Published: April 4, 2012

© 2012 Wang et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Objective: To explore feasibility and therapeutic efficacy of transnasal endoscopic resection and craniofacial resection through an external approach for olfactory neuroblastoma(ONB).

Methods: Thirty patients (twenty men and ten women) ranging in age from 12–77 years with ONB treated between 1994 and 2008 were reviewed retrospectively. All thirty cases was determined by the Kadish clinical stage, three cases with stage A, ten cases with stage B and seventeen with stage C.

Results: The patients were followed up for 3–97 months, the median follow-up time was 31 month. Sixteen patients underwent endoscopic surgery,three patients treated by combined endoscope and transcranial surgery and eleven patients treated by craniofacial resection through an external approach. The 5-year overall survival rate and the 5-year disease free survival rate of patients with transnasal endoscopic resection were 70.1% and 54.9%; for patients with craniofacial resection through an external approach, rates were 61.4% and 30.3% respectively.

Conclusion: The endoscopic approach surgery appears to be the method of choice for removing Olfactory neuroblastoma tissue as with external approaches.