gms | German Medical Science

67. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 13. Jahreskongress der Technologie- und Methodenplattform für die vernetzte medizinische Forschung e. V. (TMF)

21.08. - 25.08.2022, online

Bridging the data gap on vaccination coverage in Germany: Analysis of data on standard vaccinations, results from the German prevention index

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  • Laura Naumann - Vandage Health Economics und Analytics, Bielefeld, Germany
  • Julian Witte - Vandage Health Economics und Analytics, Bielefeld, Germany
  • Wolfgang Greiner - Universität Bielefeld, Bielefeld, Germany

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie. 67. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 13. Jahreskongress der Technologie- und Methodenplattform für die vernetzte medizinische Forschung e.V. (TMF). sine loco [digital], 21.-25.08.2022. Düsseldorf: German Medical Science GMS Publishing House; 2022. DocAbstr. 187

doi: 10.3205/22gmds136, urn:nbn:de:0183-22gmds1368

Published: August 19, 2022

© 2022 Naumann et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at



Introduction: Vaccinations are a crucial element of prevention in public health [1]. The vaccination campaigns against COVID-19 underline this aspect blatantly. Beyond COVID-19 other diseases cause a substantial burden on patients, society, and the health care system. Therefore, this work focuses on the standard vaccinations for adults in Germany as recommended by the STIKO (Ständige Impfkommission) and analyses the current state of available data. Vaccination rates on these indications are published by the Robert Koch-Institut (RKI) based on the “KV-Impfsurveillance” (vaccination surveillance by the Association of Statutory Health Insurance Physicians) once a year in the “Epidemiologisches Bulletin” [2]. This study based on the German prevention index (“Präventionsindex”) aims to summarize the available data on vaccination rates based on other data sources and identify data gaps in the current reporting of vaccination coverage.

Methods: Available coverage data on the recommended standard vaccinations for adults was extracted from the “KV-Impfsurveillance” in 2021 [3], and data on vaccination objectives were searched from other public sources. Furthermore, a systematic literature search in PubMed was conducted to study the available information on vaccination rates reported in published data analyses based on claims data. The findings of our literature review will be discussed with experts to discuss identified data gaps and the development of further vaccination coverage objectives.

Results: The data analysis from the “KV-Impfsurveillance” revealed data on 13 indications. However, more detailed information would be needed to match vaccination recommendations, for instance, differentiated by gender, (high) risk groups, or age. Defined vaccinations goals, their achievement, or benchmark values are not provided. The literature review is still ongoing. In total (excluding duplicates), the PubMed search yielded 311 results. In the next step, we will screen and analyze these 311 studies. Most publications are on Influenza, followed by pneumococcus and measles. The results show that more differentiated vaccination rates are available for many vaccinations based on claims data than currently being reported in the “KV-Impfsurveillance”. The example of influenza vaccination shows that vaccination rates differentiated by age and comorbidities show significant ranges and deviations from the mean value reported in the KV vaccination surveillance. In addition, the most widespread absence of targets for achieving specific vaccination rates is apparent.

Discussion: Currently, available evidence indicates that it is possible to draw a more differentiated picture of the vaccination coverage in Germany. However, such data is not yet available systematically and regularly, making it difficult to track the progress of vaccination rates over time.

Conclusion: Even though these are preliminary findings, our analysis highlights the need for more detailed data on vaccination coverage in Germany. Hence, an adaptive and accurate alignment of vaccination efforts on those patient groups who need it the most remains a challenge in the German health care system.

VANDAGE has received fees from Pfizer as part of the underlying study.

The authors declare that an ethics committee vote is not required.


European Union. Vaccination programmes and health systems in the European Union: Report of the Expert Panel on effective ways of investing in Health (EXPH). Luxembourg; 2018 [cited 2022 Apr 5]. Available from: External link
Robert Koch-Institut. Empfehlungen der Ständigen Impfkommission beim Robert Koch-Institut 2022. Epidemiologisches Bulletin. 2022 Jan 27;(4). Available from: External link
Robert Koch-Institut. KV-Impfsurveillance: Auswertung von Abrechnungsdaten der Kassenärztlichen Vereinigungen. 2022 [cited 2022 Apr 5]. Available from: External link