Article
Institutional conflicts of interest in studies investigating the volume-outcome relationship of clinical procedures
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| Published: | September 10, 2024 |
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Outline
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Background: Published evidence of relationships between hospital volume and outcomes for clinical procedures has led to policies aimed at centralising the provision of some of those procedures. Authors of primary studies may have an interest to influence health policy decisions by preferentially publishing research results that favour the volume category of the hospital with which they are affiliated. This can be considered a form of institutional conflict of interest (COI). Institutional COIs may compromise patient care by biasing health policy decisions.
Objective: This study aimed to explore the existence of institutional COIs in volume-outcome studies.
Methods: We used a sample of studies included in a systematic review on the hospital volume-outcome relationship in total knee arthroplasty. For studies in which at least one of the authors was affiliated with a hospital, we contacted the study authors by e-mail to obtain their institutional volume and to survey them about their opinion on institutional COIs. We categorised the study’s conclusions (positive vs. non-positive) and author’s hospital volume (high, intermediate, low). We compared conclusions for high vs. intermediate/low hospital volume categories. The survey results were analysed descriptively.
