gms | German Medical Science

70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

12.05. - 15.05.2019, Würzburg

Infection rates after ventrikuloperitoneal shunting in children with myelomeningocele – comparison of antibiotic-impregnated shunt systems versus conventional shunts

Infektionsraten nach VP-Shunt-Implantation bei Kindern mit Myelomeningocele – Vergleich zwischen antibiotika-imprägnierten und konventionellen Shunt-Systemen

Meeting Abstract

  • presenting/speaker Katharina Graf - Universitätsklinikum Gießen, Neurochirurgie, Gießen, Deutschland
  • Eberhard Uhl - Universitätsklinikum Gießen, Neurochirurgie, Gießen, Deutschland
  • Frank Patrick Schwarm - Universitätsklinikum Gießen, Neurochirurgie, Gießen, Deutschland
  • Thomas Kohl - Universitätsklinikum Mannheim, DZFT, Mannheim, Deutschland
  • Malgorzata Kolodziej - Universitätsklinikum Gießen, Neurochirurgie, Gießen, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie. Würzburg, 12.-15.05.2019. Düsseldorf: German Medical Science GMS Publishing House; 2019. DocV170

doi: 10.3205/19dgnc197, urn:nbn:de:0183-19dgnc1975

Published: May 8, 2019

© 2019 Graf et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

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Objective: CSF infection is one of the most common complications after shunt placement in children, especially in patients with former CSF infections. The goal of this study was to evaluate the rate of infection after ventriculoperitoneal (VP) shunting in patients with myelomeningocele (MMC) with regard to the implanted shunt system and the time of MMC-treatment.

Methods: Retrospective data analysis of 48 children with MMC, who had undergone VP shunt insertion between January 2010 and November 2018 in our unit. Intrauterine endoscopic patch coverage of the MMC was performed in 32 children and postnatal closure of the MMC in 16 neonates. 17 children were treated with antibiotic-impregnated (AIS) catheters and 31 children received standard (non-AIS) catheters.

Results: In our cohort of 48 childrens with a mean age of 46 (±66) days at surgery, the overall rate of shunt infection was 10.4% (5/48). One (6.3%) of the neonates, who had undergone postnatal closure of the MMC, and four (12.5%) of the intrauterine endoscopically treated fetuses had an infection of the VP shunt system. In the group of AIS-catheters 1/17 infection was detected (5.9%). Infection rate in children, who received a non-AIS was 12.9% (4/31).

Conclusion: Infection rate of VP shunt systems was lower in the group of neonates that had postnatal coverage of the MMC. The usage of AIS catheters seems to be useful to reduce infection rates in comparison to the non-AIS catheters.