Article
Early and late cranioplasty in patients that underwent decompressive craniectomy for trauma: A systematic review and meta-analysis of cohort studies
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Published: | June 9, 2017 |
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Objective: To compare occurrence of postoperative complications and mean operating time in early (< 3 months) versus late (> 3 months) cranioplasty, in trauma patients who had undergone a decompressive craniectomy (DC).
Methods: The authors present a systematic review and meta-analysis of the postoperative overall complication rate, infection rate, subdural fluid collection and operating time in cranioplasty of patients who had received a DC for trauma. The data bases PubMed, EMBASE and the Cochrane Library were systematically searched.
Results: Five cohort studies, comprising 413 patients, were included in a quantitative analysis. There was no significant difference between the early and late cranioplasty cohorts in overall postoperative complications [RR=0.68, 95%CI (0.36, 1.29), p > 0.05] and postoperative infection rate [RR=0.50, 95%CI (0.20, 1.24), p > 0.05]. Significant differences were found in postoperative subdural fluid collection [RR=0.24, 95%CI (0.07, 0.78), p<0.05] and the mean operative time [mean difference = −33.02, 95%CI (−48.19, −17.84), p < 0.05], both in favor of early cranioplasty.
Conclusion: Regarding overall postoperative complications as well as infections there was no significant difference between early and late cranioplasty. However, in early cranioplasty a significantly shorter operation time, as well as less postoperative subdural fluid collection was observed. Therefore, an early cranioplasty should be considered in these patients.