gms | German Medical Science

68th Annual Meeting of the German Society of Neurosurgery (DGNC)
7th Joint Meeting with the British Neurosurgical Society (SBNS)

German Society of Neurosurgery (DGNC)

14 - 17 May 2017, Magdeburg

Predicting of in-hospital outcome in patients with spontaneous cerebellar hemorrhage

Meeting Abstract

  • Diaa Al Safatli - Universitätsklinikum Jena, Klinik und Poliklinik für Neurochirurgie, Jena, Deutschland
  • Aaron Lawson Mclean - Universitätsklinikum Jena, Klinik und Poliklinik für Neurochirurgie, Jena, Deutschland
  • Christian Ewald - Brandenburg, Deutschland
  • Rolf Kalff - Universitätsklinikum Jena, Klinik für Neurochirurgie, Jena, Deutschland

Deutsche Gesellschaft für Neurochirurgie. Society of British Neurological Surgeons. 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS). Magdeburg, 14.-17.05.2017. Düsseldorf: German Medical Science GMS Publishing House; 2017. DocP 173

doi: 10.3205/17dgnc736, urn:nbn:de:0183-17dgnc7361

Published: June 9, 2017

© 2017 Al Safatli et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

Text

Objective: Cerebellar hemorrhage is a potentially lifethreatening condition and an understanding of the factors influencing outcome is essential for sound clinical decision-making. The aim of our to present the short-term course of patients suffering from a spontaneous cerebellar hemorrhage and to evaluate possible in-hospital outcome predictors.

Methods: We retrospectively evaluated data from 50 consecutive patients, who suffered a first spontaneous cerebellar hemorrhage (SCH) from 2009 to 2014, analyzing their short-term outcomes and identifying possible clinical, radiological and therapeutic risk factors for poor prognosis and death within 30 days.

Results: Among 50 patients with first SCH, the mean age was 72 ± 10 years. Median Glasgow Coma Scale (GCS) score on admission was 11 (IQR = 7 - 11). 19 patients (38%) underwent surgical hemorrhage evacuation with placement of an external ventricular drain (EVD), 12 patients (24%) received an EVD only and 19 patients (38) were treated conservatively. The 30-day mortality rate was 36%. In multivariate analysis only the admission GCS score was a significant predictor of 30-day mortality (OR = 0.598; 95% CI = 0.406 - 0.879; p = 0.009). For prediction of 30-day mortality, receiver operating characteristic (ROC) curve analysis confirmed that the best cut-off point was a GCS score of 10 on admission (AUC: 0.882, 95% CI = 0.717 - 1, p < 0.001).

Conclusion: Lower GCS score on admission was associated with increased 30-day mortality and poorer short-term outcome in patients with SCH. For patients with a GCS score < 10 on admission, it is important to balance the possibility of survival afforded by further therapy against the formidable risk of significant functional disability and poor quality of life.