Article
Intradural nodular fasciitis mimicking spinal glioblastoma metastasis
Search Medline for
Authors
Published: | June 9, 2017 |
---|
Outline
Text
Objective: We report the case of a 78 year old male patient who was diagnosed with a rightsided temporal glioblastoma with extensive meningeal spread at the time of diagnosis. Two months later he developed sudden onset paraplegia. An MRI scan showed a ventral space occupying lesion within the spinal canal of the thoracic segment 8 and 9 with myelon compression. An emergency decompression and resection of the alleged intradural glioblastoma metastasis was done. Surprisingly, the histopathological analysis revealed a nodular fasciitis, a reactive benign lesion typically found in soft tissue.
Methods: A clinical and histopathological description of the case ist done and compared with the current findings in the literature.
Results: Only one case of a spinal and one case of an intracranial nodular fasciitis have been reported. Both lesions were extradurally and diagnosed in otherwise young healthy individuals. This case report is the first description of an intradural nodular fasciitis. The spatio-temporal and histopathological correlation with meningeal spread of a glioblastoma are discussed.
Conclusion: This is the first description of a spinal intradural nodular fasciits. The spatiotemporal correlation suggests that the lesion may have occurred as a reaction tot he meningeal dissemination of glioblastoma cells.