gms | German Medical Science

64th Annual Meeting of the German Society of Neurosurgery (DGNC)

German Society of Neurosurgery (DGNC)

26 - 29 May 2013, Düsseldorf

Self-assessed postoperative health related quality of life of patients with frequent types of skull base meningiomas of the middle and posterior fossa

Meeting Abstract

  • Bogdan Pintea - Neurochirurgische Klinik, Universitätsklinikum Bonn
  • Peter Barbenik - Neurochirurgische Klinik, Schoen Klinik Vogtareuth
  • Julia A. Kandenwein - Neurochirurgische Klinik, Universitätsklinikum Bonn
  • Frederick H. Daher - Neurochirurgische Klinik, Universitätsklinikum Bonn
  • Rudolf A. Kristof - Neurochirurgische Klinik, Universitätsklinikum Bonn

Deutsche Gesellschaft für Neurochirurgie. 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Düsseldorf, 26.-29.05.2013. Düsseldorf: German Medical Science GMS Publishing House; 2013. DocMI.10.03

doi: 10.3205/13dgnc359, urn:nbn:de:0183-13dgnc3591

Published: May 21, 2013

© 2013 Pintea et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Objective: To evaluate the postoperative self-assessed health related quality of life (HRQoL) and its factors of influence in patients with frequent types of skull base meningiomas of the middle and posterior fossa: medial (MSM) and lateral sphenoid wing meningiomas (LSM), and petroclival (PCM) and posterior surface of the pyramid meningiomas (PPM), respectively.

Method: The SF-36 questionnaire was used to assess the present HRQoL of 184 successive surgically treated patients with above named skull base meningiomas. These data were related to their potential factors of influence retrospectively extracted from the patients’ charts.

Results: 61% of the surgically treated patients (41% MSM, 70% LSM, 65% PCM, 75% PPM) completed the SF-36 questionnaire at a median of 55 (range 10-244) months postoperatively. The overall postoperative mortality rate was 8,7% (11% PCM, 0% PPM, 4% LSM, 16% MSM). At discharge, the Karnofsky Performance Index (KPI) of patients with PCM, PPM and LSM (medians: 60, 80 and 90), who completed the SF-36 questionnaire, was not significantly different to those, who did not (medians: 60, 80, 80, p<0,144). At discharge, the KPI of patients with MSM (median: 80), who completed the SF-36 questionnaire, was significant higher compared to those, who did not (median: 80, p<0,005). The postoperative HRQoL of these patients with skull base meningiomas is lower than that of the german reference population on the scales SF1, SF5, SF6, SF7,SF8 and SF1, SF2, SF4, SF5, SF6, SF7, respectively. As assessed by the SF-36, the PCM had a poorer outcome than the PPM, on the scales SF1 and SF5. Between MSM and LSM there was no such difference. Compared to patients with MSM the HRQoL of patients with PCM was lower on the scales SF2, SF5 and SF7.

Conclusions: The postoperative mortality of PCM and MSM is higher than that of PPM and LSM. The postoperative HRQoL of these meningiomas is lower than that of the reference population. The HRQoL of PCM is lower than that of PPM, while that of MSM and LSM did not differ. The HRQoL of PCM is lower than that of MSM. The actual HRQoL of MSM may be lower, as patients who completed the SF-36 questionnaire had a somewhat higher KPI at discharge than those who did not.