Article
Polyetheretherketone cages in patients with spinal metastases undergoing postoperative radiotherapy
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Published: | April 21, 2016 |
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Background: Titanium cages are widely used in the surgical treatment of spinal metastases. In most cases adjuvant radiotherapy is an essential part of treatment. Radiation target volumes are defined from postoperative imaging. However, titanium cages lead to metal-related artifacts in imaging. Large polyetheretherketone (PEEK) cages have recently been introduced to the market as parts of corporectomy systems. PEEK does not cause imaging artifacts and may be superior to titanium cages in terms of more exact radiation planning. Our study evaluates the use of titanium and PEEK cages implanted after corporectomy.
Materials and methods: We retrospectively analyzed all cage implantations performed in our center on patients with metastatic spinal tumors between 2011 and 2015. Cases with PEEK cages were compared to titanium cages as a control group respectively. Survival data was obtained. Strong emphasis was put on the evaluation of radiation therapy concepts. Results were stratified by demographic data, tumor histology, tumor localization, pre- and postoperative Karnofsky Performance Status, oncologic concept and follow up radiographic findings.
Results: So far, fourty patients were included into the analysis comparing twenty cases of PEEK and twenty cases of titanium cage implantations. Tumor localization is 10% lumbar, 40% thoracic and 50% cervical spine. Each group shows similar distributions of demographic and oncologic features. All patients underwent radiotherapy 4-6 weeks post surgery. Radiation planning was significantly more circumscribed concerning target areas in the PEEK cage group. No case of implant failures was observed.
Conclusion: To our best knowledge this is the first study comparing the use of PEEK and titanium after corporectomy in the metastatic spine concerning postoperative radiotherapy. Due to decreased imaging artifacts radiotherapy planing is easier. A more focused radiotherapy means a decrease in target volume and associated side effects. We do feel there is a benefit towards the use of PEEK cages in spinal metastases.