gms | German Medical Science

Surgical site infections (SSIs) are defined as infections occurring up to 30 days after surgery (or up to one year after surgery in patients receiving implants) and affecting either the incision or deep tissue at the surgical site [1]. SSIs are a significant concern, as they not only lead to increased morbidity and mortality rates but also impose a considerable economic burden on healthcare systems worldwide. SSIs pose a substantial challenge to patient safety and healthcare systems worldwide. Despite advancements in surgical techniques and infection control measures, SSIs continue to occur at an alarming rate. SSIs are responsible for approximately $3.5 billion to $10 billion in US healthcare costs annually. Compared to patients without SSIs, those with SSIs remain in the hospital approximately 7 to 11 days longer; one study involving 177,706 postsurgical patients reported that SSI was the cause of 78% of all readmissions [2]. Therefore, measures to reduce surgical site infection are necessary [3] and must be adaptedunder pandemic situations [4].

The proposed 3-step model integrates perioperative measures, multidisciplinary collaboration, and continuous quality improvement (CQI) initiatives to enhance patient safety and outcomes.

This subsection emphasizes the importance of adhering to evidence-based guidelines for infection prevention during surgical procedures. It explores preoperative strategies (e.g., patient optimization, antimicrobial prophylaxis), intraoperative measures (e.g., sterile technique adherence), and postoperative care (e.g., wound management) [1].

Preoperatively identifying and addressing modifiable risk factors such as obesity, smoking cessation programs, glycemic control in diabetic patients, and decolonization of nasal carriers of Staphylococcus aureus can significantly reduce the risk of SSIs.

Administering appropriate antimicrobial prophylaxis based on established guidelines is crucial in preventing SSIs.

Proper skin preparation using residually-acting alcohol-based formulations that contain e.g. povidone-iodine or chlorhexidine gluconate, significantly reduces bacterial colonization at the surgical site.

Adherence to strict aseptic techniques during surgery minimizes contamination risks.

Wearing appropriate surgical attire including sterile gowns and gloves reduces the introduction of pathogens into the surgical field [5].

The use of sterile surgical drapes creates a barrier between the surgical site and potential sources of contamination.

Antiseptic irrigation solutions, such as polyhexanide or povidone-iodine, can be used intraoperatively to reduce bacterial load at the surgical site.

Proper wound care techniques, including regular dressing changes and monitoring for signs of infection, are essential in preventing SSIs.

Encouraging early mobilization postoperatively aids in improving blood circulation and reducing the risk of infection.

Rational use of antibiotics, including appropriate duration and selection based on culture results, helps prevent the development of antibiotic-resistant organisms.

Surgeons play a pivotal role in preventing SSIs, for instance, through appropriate antimicrobial prophylaxis, meticulous surgical technique, and timely wound closure. Collaborative efforts with other healthcare professionals can enhance compliance with these practices and promote standardized protocols.

Nurses are integral members of the multidisciplinary team involved in perioperative care. Their contributions include preoperative patient education, strict adherence to aseptic techniques during surgery, effective wound management postoperatively, and surveillance for early detection of SSIs.

Anesthesia providers contribute significantly to SSI reduction by optimizing patients’ physiological status before surgery, ensuring normothermia during procedures, and implementing strategies such as antibiotic stewardship programs that minimize the risk of infection.

Infection prevention specialists play a critical role in developing comprehensive infection control programs tailored to each surgical setting’s unique needs. Their involvement includes surveillance, monitoring compliance with infection control practices, and providing education and training to healthcare professionals.

Environmental services personnel play a crucial role in maintaining a clean and hygienic surgical environment. Their collaboration with the multidisciplinary team ensures proper cleaning and disinfection surfaces and validated reprocessing of surgical equipment.

Information technology systems can facilitate communication, enhance data collection, and support decision-making processes related to SSI prevention. Collaborative efforts between healthcare professionals and IT specialists can lead to the development of innovative tools for real-time monitoring, risk assessment, intervention implementation and auditing [3].

Engaging patients in their care is vital for SSI reduction. Educating patients about preoperative hygiene measures, promoting adherence to prescribed medications, and involving them in shared decision-making processes can empower patients to actively participate in infection prevention.

To sustain long-term improvements in SSI rates, this subsection emphasizes the importance of CQI initiatives. It explores the use of surveillance systems, data analysis, feedback mechanisms, and regular audits to identify areas for improvement and implement targeted interventions.

Various methodologies are utilized in CQI initiatives to reduce SSIs. This section explores the application of Lean Six Sigma principles, Plan-Do-Study-Act cycles, root cause analysis, process mapping, and other quality improvement tools in different healthcare settings.

This section presents a comprehensive analysis of the outcomes associated with CQI initiatives aimed at reducing SSIs. It examines reductions in SSI rates, improvements in compliance with infection prevention protocols, enhanced patient satisfaction scores, decreased length of hospital stays, and cost savings achieved through these initiatives.

In conclusion, SSIs remain a significant concern in operating rooms worldwide. However, by implementing a comprehensive model that integrates perioperative measures, multidisciplinary collaboration, and CQI initiatives, healthcare institutions can effectively decrease the incidence of SSIs and improve patient outcomes.

The authors declare that they have no competing interests.

• Saeid Amini Rarani: 0000-0003-4700-0211
• Axel Kramer: 0000-0003-4193-2149