gms | German Medical Science

26. Jahrestagung der Deutschen Retinologischen Gesellschaft

Deutsche Gesellschaft für Retinologie

27.09.2013, Hamburg

Circulating Melanoma Cells: An evolving instrument in the diagnostic of uveal melanoma

Meeting Abstract

Suche in Medline nach

  • Salvatore Grisanti - Lübeck, Germany
  • J. Lüke - Lübeck, Germany
  • M. Reinsberg - Lübeck, Germany
  • A. Tura - Lübeck, Germany

Retinologische Gesellschaft. 26. Jahrestagung der Retinologischen Gesellschaft. Hamburg, 27.-27.09.2013. Düsseldorf: German Medical Science GMS Publishing House; 2013. Doc13rg27

doi: 10.3205/13rg27, urn:nbn:de:0183-13rg271

Veröffentlicht: 20. August 2013

© 2013 Grisanti et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

We previously determined the presence of circulating melanoma cells (CMCs) in uveal melanoma patients without metastatic disease and correlated the presence with other prognostic risk factors. The aim of this study was to further evaluate CMCs in uveal melanoma patients as diagnostic and prognostic tool. Successful identification of circulating tumor cells was correlated with characteristics of the primary tumor and cultured cells. Different markers were evaluated both in the primary tissues as well as in the propagated cultured cells. A good correlation between the examined tissue and cell samples was shown. The detection of CMCs is a useful tool for prognostic evaluation and determination of therapeutic strategies.