Artikel
Antimicrobial polymer surfaces prepared by two combined plasma procedures – high power impulse magnetron sputtering (HiPIMPS) and plasma based ion implantation (PBII)
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Autoren
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Antje Quade
- Leibniz-Institut für Plasmaforschung und –technologie INP e.V. Greifswald, Abteilung Plasmaoberflächentechnologie, Greifswald
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Frank Hempel
- Leibniz-Institut für Plasmaforschung und –technologie INP e.V. Greifswald, Abteilung Plasmaoberflächentechnologie, Greifswald
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Birgit Finke
- Leibniz-Institut für Plasmaforschung und –technologie INP e.V. Greifswald, Abteilung Plasmaoberflächentechnologie, Greifswald
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Klaus-Dieter Weltmann
- Leibniz-Institut für Plasmaforschung und –technologie INP e.V. Greifswald, Abteilung Plasmaoberflächentechnologie, Greifswald
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Maik Fröhlich
- Leibniz-Institut für Plasmaforschung und –technologie INP e.V. Greifswald, Abteilung Plasmaoberflächentechnologie, Greifswald
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Martin Polak
- Leibniz-Institut für Plasmaforschung und –technologie INP e.V. Greifswald, Abteilung Plasmaoberflächentechnologie, Greifswald
| Veröffentlicht: | 30. September 2016 |
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Gliederung
Text
The surface finishing of medical products with anti-microbial properties is crucial for their future use in patients to reduce or prevent nosocomial infections and thus also arising costs by prolonged stays in hospital. A very high anti-microbial effect against the majority of germs show the elements copper or silver [1], [2], [3], [4] compared to conventional antibiotics or antiseptics. No resistances were found until now. Usually the enrichment of the polymers with silver or copper nanoparticles or Sol-Gel derived coatings are used as preparation methods.
More sophisticated are plasma based processes like High Power Impulse Sputtering (HiPIMS) [5] in combination with Plasma Based Ion Implantation (PBII) [6]. These are comparatively new methods with high application potential and many advantages.
We used in our study both plasma methods HiPIMS & PBII for the deposition and implantation of copper and determined the properties in detail. The chemical surface composition and also the depth profile of the copper implantation was analysed by XPS (X-ray photoelectron spectroscopy) and XRD (X-ray diffraction). The surface morphology and roughness was investigated by AFM.
The combination of HiPIMS and PBII show very promising results: The deposition rate is higher compared to the application of HiPIMS processes alone. The roughness of the polymer surface (here ABS – acrylonitrile-butadiene-styrene) is decreased whereas the size of the copper crystallites increased. Of particular importance in this context is the fact that for instance only a 1 min plasma treatment of complex 3D-shaped medical products lead to an anti-microbial efficiency for the germ inactivation shown in a reduction of at least 6 log-stages (see Figure 1 [Fig. 1]).
References
- 1.
- Finke B, Polak M, Hempel F, Rebl H, Zietz C, Stranak V, Lukowski G, Hippler R, Bader R, Nebe JB, Weltmann KD, Schröder K. Antimicrobial potential of copper containing titanium surfaces generated by ion implantation and dual high power impulse magnetron sputtering. Adv Eng Mater. 2012;14(5):B224-B230. DOI: 10.1002/adem.201180054
- 2.
- Chen W, Liu Y, Courtney HS, Bettenga M, Agrawal CM, Bumgardner JD, Ong JL. In vitro anti-bacterial and biological properties of magnetron co-sputtered silver-containing hydroxyapatite coating. Biomaterials. 2006 Nov;27(32):5512-7. DOI: 10.1016/j.biomaterials.2006.07.003
- 3.
- Hempel F, Finke B, Zietz C, Bader R, Weltmann KD, Polak M. Antimicrobial surface modification of titanium substrates by means of plasma immersion ion implantation and deposition of copper. Surf Coat Technol. 2014;256:52-8. DOI: 10.1016/j.surfcoat.2014.01.027
- 4.
- Heidenau F, Mittelmeier W, Detsch R, Haenle M, Stenzel F, Ziegler G, Gollwitzer H. A novel antibacterial titania coating: metal ion toxicity and in vitro surface colonization. J Mater Sci Mater Med. 2005 Oct;16(10):883-8. DOI: 10.1007/s10856-005-4422-3
- 5.
- Stranak V, Čada M, Quaas M, Block S, Bogdanowicz R, Kment Š, Wulff H, Hubička Z, Helm C, Tichy M, Hippler R. Physical properties of homogenous TiO2 films prepared by high power impulse magnetron sputtering as a function of crystallographic phase and nanostructure. J Phys D: Appl Phys. 2009;42:105204 (12pp).
- 6.
- Polak M, Quade A, Weihe T, Hempel F, Weltmann KD. Combination of plasma based ion implantation and deposition (PBII&D) and high power impulse magnetron sputtering (HiPIMS) for the development of antimicrobial surfaces on polymers [Abstract 1b1633-OR]. In: 14 th International Conference on Plasma Surface Engineering – PSE 2014; September, 15–19, 2014; Garmisch-Partenkirchen.
