Artikel
Laryngopharyngeal reflux – the unusual suspect
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Veröffentlicht: | 15. April 2013 |
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Gliederung
Text
Laryngopharyngeal reflux (LPR) refers to the backflow of stomach contents into the hypopharynx and larynx. It differs from classical gastroesophageal reflux disease (GERD) in many ways. Proton pump inhibitors (PPI) have become the treatment of choice but there are significant controversies concerning their effectiveness.
Aim: To evaluate the effectiveness of PPI for treatment of LPR
Material and methods: We conducted a prospective study of 50 patients with LPR, diagnosed by reflux finding score (RFS) and reflux symptom index (RSI). We used fibrolaryngoscopy to evaluate the influence of 16 week PPI treatment on RFS and RSI.
Results: 43 patients (86%) improved after PPI treatment.
Conclusion: The reflux finding score and reflux symptom index are very helpful for diagnosing LPR. In cases where LPR is the cause of the laryngeal symptoms PPI are effective, when administered in high doses for 2–4 months.
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