Artikel
New drug targets for the treatment of co-morbid multifunctional diseases
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Veröffentlicht: | 6. September 2019 |
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Gliederung
Text
During the realization of the “Trilateral Partnership – Cooperation Project” between Scholars and Scientists from Ukraine (Kiev), Russia (Tomsk and Novosibirsk) and Germany (Bielefeld) (2016-2018) we have obtained important data and results concerning pathogenetic factors of such important comorbidity as combination of hypertension and asthma. The relevant medical data and medical part of this project presenting the focus to asthma and hypertension was done in TOMSK. Based on this data the computational part was done in NOVOSIBIRSK. Using new textmining tools relevant target genes could be identified. For further discussion the target gene IL10 was discussed in KIEV based on knock out experiments. Using methods of database integration and information fusion the new information system GenCoNet could be implemented representing the positive and negative drug list of asthma and hypertension.
This project was supported by the VolkswagenStiftung.
The authors declare that they have no competing interests.
The authors declare that an ethics committee vote is not required.
References
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