Artikel
Comparison of longevity of battery life between Kinetra and Activa PC neurostimulators (Medtronic) for Deep Brain Stimulation
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Veröffentlicht: | 8. Juni 2016 |
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Objective: Throughout the last 20 years, Deep Brain Stimulation (DBS) has become an approved therapy in Parkinson's Disease, Essential Tremor, Dystonia and Obsessive Compulsive Disorder. Several systems for DBS are on the market, but the main percentage of systems implanted for DBS therapy are supplied by Medtronic Inc. (Meerbusch, Germany). At the moment neurostimulators of the Activa-product-family (Medtronic Inc., Meerbusch, Germany) are available. Kinetra neurostimulators (Medtronic Inc., Meerbusch, Germany) have been implanted before but are not available any more. Subjective impressions of implanting neurosurgeons and patients now suggest, that the longevity of battery life of Activa PC neurostimulators is shorter than that of Kinetra neurostimulators.
Method: In this retrospective study we evaluated our Deep Brain Stimulation database of all patients that received a system for DBS or a replacement of a neurostimulator in our neurosurgical clinic. We compared the longevity of battery life of all initially implanted neurostimulators (Kinetra vs. Activa PC), which means all those neurostimulators that have been implanted initially after electrode placement. Furthermore, we compared the overall longevity of all implanted neurostimulators.
Results: Based on the DBS database of our clinic (between years 2002-2015), we included 42 Kinetra neurostimulators that have been implanted initially with the electrode implantation, and 17 initial Activa PC neurostimulators in our analysis. Battery life of initailly implanted Kinetra neurostimulators was significantly longer than that of Activa PC neurostimulators (median 68.5 months vs. 42 months; p < 0.001). The median battery life of all implanted Kinetra stimulators (n = 63) was also significantly longer than Activa PC (n = 29) longevity (64 vs. 38 months; p < 0.001).
Conclusions: In this retrospectively analyzed cohort battery life of Kinetra neurostimulators was significantly longer than that of Activa PC neurostimulators. Due to the small sample size, validity of the results is limited.