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67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

12. - 15. Juni 2016, Frankfurt am Main

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Age-related differences in subjective and objective measures of pain, functional impairment and health-related quality of life in lumbar degenerative disc disease

Meeting Abstract

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  • Marco V. Corniola - Department of Neurosurgery and Faculty of Medicine, University Hospital Geneva, Geneva, Switzerland
  • Martin N. Stienen - Department of Neurosurgery and Faculty of Medicine, University Hospital Geneva, Geneva, Switzerland; Department of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, Switzerland
  • Nicolas R. Smoll - Department of Neurology, John Hunter Hospital, Newcastle, Australia
  • Karl Schaller - Department of Neurosurgery and Faculty of Medicine, University Hospital Geneva, Geneva, Switzerland
  • Oliver P. Gautschi - Department of Neurosurgery and Faculty of Medicine, University Hospital Geneva, Geneva, Switzerland

Deutsche Gesellschaft für Neurochirurgie. 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS). Frankfurt am Main, 12.-15.06.2016. Düsseldorf: German Medical Science GMS Publishing House; 2016. DocDI.17.05

doi: 10.3205/16dgnc200, urn:nbn:de:0183-16dgnc2007

Veröffentlicht: 8. Juni 2016

© 2016 Corniola et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: Demographic changes will lead to an increase of elderly people in our population and to a higher prevalence of patients suffering from degenerative disc disease (DDD) consecutively. The goal of this study was to investigate age-related differences in subjective and objective measures of pain, functional impairment and health-related quality of life (HRQoL) in patients with lumbar DDD.

Method: In a prospective two-center study, back and leg pain intensity (visual analogue scale (VAS)), functional disability (Oswestry Disability Index (ODI), Roland-Morris Disability Index (RMDI)) and HRQoL (EuroQol-5D (EQ5D), Short-Form (SF12)) were collected for consecutive patients undergoing lumbar spine surgery to assess subjective functional impairment (SFI). Objective functional impairment (OFI) was estimated using the timed-up-and-go (TUG) test. Study groups were built according to age less than 65 or 65 and over.

Results: A total of n=329 patients (n=137 females, 41.6%) with a mean age of 58.4 years (standard deviation (SD) 15.5) were included. Patients less than 65 years (n=200, 60.8%) reported significantly higher VAS leg pain (5.4 vs. 4.4, p=0.002) than patients of 65 years and over (n=129, 39.2%), whilst there was no difference in VAS back pain. Younger patients had a higher functional impairment (RMDI 12.3 vs. 10.9, p=0.008). Regarding HRQoL, both EQ5D Index (0.501 vs. 0.410, p=0.001) and SF12 Mental Component Score (MCS; 45.2 vs. 40.8, p=0.001) were significantly better in the older age group. Younger patients showed more OFI (TUG-test t-score 135.3 vs. 115.8, p<0.0001). In univariate analysis, patients less than 65 years were 3.5 times as likely as 65 years old and over patients to show OFI (OR 0.29, 95% CI 0.18-0.49, p<0.001). Once this analysis was corrected for baseline group differences, the relationship was slightly attenuated, but remained significant (OR 0.42, 95% CI 0.21-0.84, p=0.014).

Conclusions: The TUG test, as a standardized approach to the measurement of OFI, provides a better option than non-standardized tests of SFI when measuring and comparing the functional impairment of patients in different age groups.