Artikel
Primary cerebral malignant melanoma with whole spinal metastasis
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Autoren
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Ilker Solmaz
- Department of Neurosurgery, Gulhane Military Medical Academy, Ankara, Turkey
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Yunus Kaçar
- Department of Neurosurgery, Gulhane Military Medical Academy, Ankara, Turkey
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Çaglar Temiz
- Department of Neurosurgery, Gulhane Military Medical Academy, Ankara, Turkey
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Mehmet Daneyemez
- Department of Neurosurgery, Gulhane Military Medical Academy, Ankara, Turkey
| Veröffentlicht: | 13. Mai 2014 |
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Gliederung
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Objective: Primary cerebral malignant melanoma is very rare and usually treated with surgical intervention. Spinal seeding is not previously reported. In this report, we present a case of primary cerebral malignant melanoma who underwent surgical treatment and died after spinal seeding.
Method: 20-year-old male patient presented with headache and fatigue. Magnetic resonance imaging of the patient showed left frontal hyperintense mass lesion. The patient underwent surgical treatment with left frontal craniotomy and the tumor was subtotally removed because of massive hemorrhage and close relationship with the speech area. No neurological deficit occured after surgery.
Results: Histological examination of the specimens revealed the diagnosis of malignant melanoma. The physical examination of the whole body of the patient showed that there was no skin or cutaneous lesion on the patient. Radiotherapy and chemotherapy were performed to the patient. Tetraparesis developed 6 month after surgery and the spinal magnetic resonance imaging of the patient showed tumor seeding into the whole spinal intradural space. The patient died 1 month after the spinal seeding.
Conclusions: Primary cerebral malignant melanoma should be removed totally if possible. Spinal seeding may develop after surgery. Radiotherapy or chemotherapy has no significant effect on the treatment of central nervous system malignant melanoma.
