gms | German Medical Science

64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

26. - 29. Mai 2013, Düsseldorf

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Clinical and radiological outcome following anterior cervical discectomy and fusion with Stand-alone PEEK Cages with or without Osteogenic Filling Substance: a retrospective matched-pair analysis

Meeting Abstract

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  • Ehab Shiban - Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, München, Deutschland
  • F. Schwarm - Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, München, Deutschland
  • Maria Wostrack - Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, München, Deutschland
  • Sandro M. Krieg - Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, München, Deutschland
  • Bernhard Meyer - Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, München, Deutschland
  • Jens Lehmberg - Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, München, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC). Düsseldorf, 26.-29.05.2013. Düsseldorf: German Medical Science GMS Publishing House; 2013. DocMO.20.08

doi: 10.3205/13dgnc180, urn:nbn:de:0183-13dgnc1808

Veröffentlicht: 21. Mai 2013

© 2013 Shiban et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

Text

Objective: To evaluate the influence of demineralized bone matrix (DBM) on long-term results after anterior cervical discectomy and fusion (ACDF) with stand-alone PEEK cages.

Method: A retrospective age-, gender-, symptoms- and level-matched pair analysis was performed on 20 pairs of patients who underwent anterior cervical discectomy and fusion (ACDF) with stand-alone PEEK cages with a minimum follow-up of 12 months. In the study group, DBM was used as an osteogenic filling substance. Radiographic follow-up included static and flexion/extension radiographs. Changes in the operated segments were measured and compared to radiographs directly after surgery. Clinical outcome was evaluated by a physical exam, pain VAS and the EuroQOL questionnaire (EQ-5D).

Results: Fusion rate in the study group was 85% and 88% the control group (P = 0.994). Subsidence rate in the study group was 20% and 30% in the control group (P = 0.715). Cervical alignment improved in 10% and 5%, worsened in 5% and 15% and remained same in 85% and 80% in the study and control group, respectively. Pain VAS declined from 6 ± 2 to 3 ± 2 in the study group (P <FONT face=Symbol>£ </FONT>0.001) and from 7 ± 3 to 2 ± 3 (P <FONT face=Symbol>£ </FONT>0.001) in the control group. In the study group the percentage of patients reporting problems declined in comparison between prior to surgery and at follow-up in all dimensions of the EuroQOL questioner as follows: mobility from 45% to 15% and 55% to 25%; self-care: from 35% to 5% and 35% to 15%; usual activities: from 90% to 30% and 80% to 40%; pain/discomfort: from 95% to 50% and 95% to 80%; anxiety/depression: from 65% to 25% and 45% to 35% in the study and the control group, respectively. VAS Overall Health increased from 53 ± 26 to 79 ± 17 in the study group (P = 0.001) and from 50 ± 21 to 70 ± 23 (P = 0.006) in the control group.

Conclusions: Application of DBM for ACDF with stand-alone PEEK Cages has no statistically significant influence on radiological or clinical Outcome.