gms | German Medical Science

56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
3èmes journées françaises de Neurochirurgie (SFNC)

Deutsche Gesellschaft für Neurochirurgie e. V.
Société Française de Neurochirurgie

07. bis 11.05.2005, Strasbourg

Gender-related differences in incidence and morbidity of subarachnoid hemorrhage and/or cerebral aneurysms

Geschlechtsspezifische Unterschiede in der Inzidenz und Morbidität von Patienten mit Subarachnoidalblutung und/oder zerebralen Aneurysmen

Meeting Abstract

  • corresponding author A. Woszczyk - Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt am Main
  • M. Setzer - Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt am Main
  • J. Beck - Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt am Main
  • H. Vatter - Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt am Main
  • A. Raabe - Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt am Main
  • V. Seifert - Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt am Main

Deutsche Gesellschaft für Neurochirurgie. Société Française de Neurochirurgie. 56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC). Strasbourg, 07.-11.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc10.05.-15.04

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dgnc2005/05dgnc0166.shtml

Veröffentlicht: 4. Mai 2005

© 2005 Woszczyk et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

Femal gender is a recognized risk factor for occurrence of aneurysmal subarachnoid hemorrhage (SAH). Futhermore it is presumed, that females have a higher risk for development of cerebral vasospasm. The influence of the gender aneurysmal disease is not examined completely.

Methods

Over a period of 5 years from January 2000 to December 2004, 621 with SAH and/or cerebral aneurysms were seen. 540 patients had 677 cerebral aneurysms, they were treated with either microsurgical operation or endovascular coiling. 62 patients (10%) had none aneurysmal SAH. Angiography were not performed 19 patients (3%), because of their poor condition in at admission. Retrospective analysis of differences dependend on gender in admission characteristics, course of illness, and outcome between 365 womens (59%) and 256 men (41%) with cerebral aneurysm and/or SAH.

Results

The female to male ratio was 1,5:1. There was not difference with regard to the age, Fisher and WFNS score by admission. Female patients harbored aneurysms of the ACI more frequently than male patients (70% vs. 30%, p<0,001). Multiple aneurysms were more often in femals (33% vs. 20%, p><0,05). Only clinical vasospasm occure more frequent in womens (OR1,5, p<0,05), angiographical vasospasm and infarction due to vasospasm were comparable in both groups. There was not indeed any difference in the occurrence of the acute hydrocephalus, however the men needed more frequently an shunt (15% vs. 21%, p<0,05). Poor outcome rates at 6 month were not statistically different between the genders after adjustment of the WFNS and Fisher score at admission. The aneurysm of females were coiled frequently (40% vs. 27%, p<0,05), non gender diffenrece in the frequence of surgery.

Conclusions

We have demonstrated gender differences in the development of clinical vasospasm, the incidence of multiple aneurysms, location of aneurysms, and requirement of permanent CSF-shunt. The indentification of these differences is an important subject for futher research.