gms | German Medical Science

25th Annual Meeting of the German Retina Society

German Retina Society

01.06. - 02.06.2012, Münster

Improved interpretation of fourier domain optical coherence tomography (FD-OCT) using c-scan technique in wet age related macular degeneration (AMD)

Meeting Abstract

  • Christoph Kernstock - Universitäts-Augenklinik Tübingen
  • W. Inhoffen - Universitäts-Augenklinik Tübingen
  • K.U. Bartz-Schmidt - Universitäts-Augenklinik Tübingen

German Retina Society. 25th Annual Conference of the German Retina Society. Münster, 01.-02.06.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12rg29

doi: 10.3205/12rg29, urn:nbn:de:0183-12rg297

This is the translated version of the article.
The original version can be found at:

Published: May 30, 2012

© 2012 Kernstock et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Introduction: New volume mode of the Spectralis-OCT (Heidelberg Engineering, Dossenheim) allows a distance as little as 11 µm between adjacent b-scans. So far, there is no experience regarding interpretation of c-scans that can be acquired using this technique.

Methods: OCT volume scans were acquired in 52 Patients with AMD and choroidal neovascularizations (CNV) with horizontal orientation of the RPE line. Virtual cross-sections through the volume dataset parallel to the retinal layers were reconstructed. Corresponding b-scans were shown separately and compared to the c-scans.

Results: Shadows of retinal vessels showed minimal offset between b-scans, allowing accurate acquisition of volume scans sufficient for c-scan visualization. Three different patterns were observed regarding retinal layers when scrolling through the volume (from inner towards outer retina): a) straight pattern: lines representing retinal layers moving from one side towards the other. b) concave pattern: lines on one side were mirrored on the opposite side and moving towards image center. c) convex pattern: lines running from center outwards. Considering these patterns, vessels of CNV or fibrovascular membranes, drusen and cystic alterations were detectable and could be correlated to other structures in 40/52 patients.

Conclusion: Volume scans with 11 µm lateral resolution provide improved images of pathologies in AMD. The planar visualization improves the assessment of the extent of pathologies in comparison to b-scans. However, interpretation of corresponding b-scans is still necessary to avoid misinterpretations of structures in c-scans.