gms | German Medical Science

27. Wissenschaftlicher Kongress der Deutschen Hochdruckliga

Deutsche Liga zur Bekämpfung des hohen Blutdrucks – Deutsche Hypertonie Gesellschaft e. V.

26. bis 29.11.2003, Bonn

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Blood pressure response during abpm and exercise and cardiac alterations

Blutdruck während ABDM und Ergometrie und Anpassugen des Herzens

Meeting Abstract (Hypertonie 2003)

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  • presenting/speaker I.W. Franz - Klinik Wehrawald der BfA (Todtmoos, D)
  • J.F.M. Müller - Klinik Wehrawald der BfA (Todtmoos, D)

Hypertonie 2003. 27. Wissenschaftlicher Kongress der Deutschen Hochdruckliga. Bonn, 26.-29.11.2003. Düsseldorf, Köln: German Medical Science; 2004. Doc03hochP63

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/hoch2003/03hoch163.shtml

Published: November 11, 2004

© 2004 Franz et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Background

Some studies with a small sample size suggested that left ventricular mass index (LVMI) is more closely related to ambulatory blood pressure (ABPM) or exercise BP (ExBP) than to resting/casual BP.

Methods

In 1142 untreated patients (mean age 50.0±9.2 y., 567 males) an ABPM (SpaceLabs 90207), a bicycle exercise test (50-100watts, 5 min recovery period) and an echocardiography were performed within a 48 h period and thereafter the patients were divided into 4 groups (G1-4; [Fig. 1]) due to their BP response.

Results

Despite a normotensive daytime BP during ABPM, patients of G2 with an increased ExBP (ExBP+, >200/>100 mmHg at 100 watts) revealed significantly (p<0.05 - p<0.001) higher values for LVMI, wall thickness (IVS, PWT) left ventricular enddiastolic dimension (LVID), left atrial size (LA) and a disturbed diastolic function (E/A<1) compared to G1 (normal ExBP, ExBP-) and comparable values to G3 (daytime ABPM hypertensive >135/85, EXBP-).

Conclusions

These data suggest that exercise BP may be an important determinant for cardiac alterations even in patients with a normotensive response during ABPM.