gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Inflammation and age-related macular degeneration

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  • corresponding author S. Fauser - Department of Vitreoretinal Sugery, Center of Ophthalmology, University of Cologne

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.11.06

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Fauser.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Several studies show that inflammation is involved in the formation of drusen and choroidal neovascularization in AMD. However, there is some controversy about the relevance of these processes in human AMD as most of the data was found in a laser-induced model of choroidal neovascularization. In this model, a primary inflammation in response to the laser injury triggers the choroidal neovascularization. Although this model captures many of the important features of the human disease, it also may involve processes not present in AMD. The role of inflammation in AMD and the relevance of the experimental data will be discussed.