gms | German Medical Science

21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem
8. Symposium der International Society of Ocular Trauma

Deutsche Gesellschaft für Retinologie
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

Central Retinal Vein Occlusion (CRVO) without Retinal Vasculitis in Wegener's Granulomatosis

Meeting Abstract

Suche in Medline nach

  • Bernhard M. Stoffelns - Mainz/Germany
  • C. Kramann - Mainz/Germany
  • K. Schoepfer - Mainz/Germany

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008V131

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Veröffentlicht: 18. Juni 2008

© 2008 Stoffelns et al.
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Background: To describe a patient with Wegener's Granulomatosis, who developed unilateral Central Retinal Vein Occlusion (CRVO) without clinical evidence of intraocular inflammation.

Methods: A 54-year-old man developed unilateral non-ischemic CRVO associated with systemic Wegener's Granulomatosis, which had been in remission since one year. Fluorescein angiography revealed no sign of retinal vasculitis. Visual acuity was reduced to 6/10 due to diffuse macular edema. No other vascular risk factors were identified. Isovolemic hemodilution and systemic immunosuppression with prednisolon oral were initiated.

Results: After 3 months the diffuse leckage at the posterior pole was reduced, but vision dropped to 2/10 due to development of cystoid macular edema. 3 months after grid laser photocoagulation leckage was significantly reduced and vision improved to 3/10. 4 months after intravitreal injection of 10 mg triamcinolone acetonide no further leckage in the macular was detected and vision was stabilized at 5/10.

Conclusions: Wegener`s Granulomatosis should be considered in the differential diagnosis of CRVO in the young age group. In those patients intravitreal triamcinolone acetonide seems to be a good adjunct to systemic immunosuppressive therapy. Only 5 cases with isolated CRVO in Wegener´s granulomatosis have been reported in literature so far. In these patients the lack of clinical evidence of retinal vasculitis was explained by a postulated compression of the central retinal vein in a laminar or retrolaminar location by extracapillary granulomatous inflammation.Financial interests of the authors are disclosed.