gms | German Medical Science

83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

16.05. - 20.05.2012, Mainz

Postoperative change of microbial flora in the wound bed under antibiosis

Meeting Abstract

  • corresponding author Doris Bücher-Ollig - Bundeswehrkrh., HNO-Abt., Koblenz, Germany
  • presenting/speaker Roland Jacob - Zentr. Inst. der Bundeswehr, Koblenz, Germany
  • presenting/speaker Edmond Kurig - Zentr. Inst. der Bundeswehr, Koblenz, Germany
  • presenting/speaker Rainer Treude - Bundeswehrzentralkrankenhaus, Koblenz, Germany

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. 83rd Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. Mainz, 16.-20.05.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12hno11

DOI: 10.3205/12hno11, URN: urn:nbn:de:0183-12hno111

Veröffentlicht: 23. Juli 2012

© 2012 Bücher-Ollig et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Introduction: While peri- or postoperative treatment with antibiotic agents is standard practice today, little is known about the postoperative development of the flora in wound beds. It is unclear to which extent the normal flora is affected by the treatment with antibiotics. Moreover it is unknown if the prophylaxis may cause a potential shift in the microbial spectrum.

The healthy flora of the nose and paranasal sinus consists of aerobic and anaerobic, e.g. staphylococcus and streptococcus.

Method: Patients planed for an elective paranasal sinus operation are perioperatively treated with clindamycin 600 mg. Preoperative, two and seven days after the surgery, samples taken from within the nose using smear tests were tested microbiologically.

Results: A total of 22 patients ranging from 23 to 57 years of age have been tested. None of them took an immunomodulatory agent.

The untreated flora identified by the analysis was without any pathologicals findings and included anaerobics, staphylococcus, streptococcus and neisseriae as expected.

During the observation period the spectrum of flora did not change.

Conclusion: The static nature of the observed microbial flora suggests that the application of antibiotic agents as a matter of routine may not be required. Otherwise it appears, that the treatment does not support the development of a pathological flora either. In addition the results show, that in case of a postoperative infection standard antibiotics can be used, instead of a postoperative flora adapted antibiotics, since there is no change. In the future we will compare the spectra of patients treated with antibiotics to non treated samples in a double blind study.