gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Retrobulbar haemodynamic before and after oculopression

Meeting Abstract

Suche in Medline nach

  • corresponding author K. Huber - Universitäts-Augenklinik Aachen
  • A. Remky - Universitäts-Augenklinik Aachen

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogP 096

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog587.shtml

Veröffentlicht: 22. September 2004

© 2004 Huber et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

Multiple pharmacological studies claim that there are no vascular changes due to intraocular pressure (IOP) reduction alone. In our study we induced a decrease of the IOP by oculopression. Its effect on the retrobulbar haemodynamic was studied by means of colour Doppler imaging.

Methods

17 patients (age 72±8; 7f, 10m), prepared for cataract surgery, were included in a prospective study. Before and after 5 minutes of oculopression the IOP was measured by Tonopen (Technomed). Colour Doppler imaging (Siemens Sonoline Sienna) was used to determine the peak systolic (PSV) and end-diastolic velocities (EDV) as well as resistive Index (RI) before and after oculopression in the ophthalmic artery (OA), the central retinal artery (CRA), the central retinal vein (CRV), the temporal short ciliar arteries (TPCA) and the nasal short ciliar arteries (NPCA).

Results

After oculopression there was a significant reduction of the IOP of 4.5 mmHg (p<0,0001). Colour Doppler imaging showed a significant increase of the PSV after oculopression in all studied vessels (OA by 8%, p<0.02; CRA by 15%, p<0.0001; CRV by 22%, p<0.0001; TPCA by 12%, p<0.0001; NPCA by 18%, p<0.0001). After oculopression EDV had also a significant increase (CRA by 17%, p<0.0015; CRV by 13%, p<0.0017; NPCA by 14%, p<0.049). The RI of the studied vessels showed no significant changes before and after oculopression.

Conclusions

Oculopression induced a significant IOP reduction. Furthermore, there is an increase of the flow velocities of the retrobulbar vessels, this may be due to an increase of perfusion pressure. This aspect is important for pharmacological studies with topical antiglaucoma medication, concerning their vascular effects on retrobulbar vessels.