gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Experiences with high density-silicone oil in vitreoretinal surgery

Meeting Abstract

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  • corresponding author M. A. D. Tilanus - University Medical Centre Nijmegen, The Netherlands
  • B. J. Klevering - University Medical Centre Nijmegen, The Netherlands
  • T. Theelen - University Medical Centre Nijmegen, The Netherlands

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSO.01.07

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Veröffentlicht: 22. September 2004

© 2004 Tilanus et al.
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The use of a novel kind of high-density silicone oil (Oxane HD) has recently been suggested as intraocular tamponade in complicated retinal detachment. We observed a number of serious side-effects in eyes operated on with this type of silicone oil.


We evaluated 20 eyes of 19 patients who underwent pars plana vitrectomy with membrane peeling and intraocular tamponade with high-density silicone oil for complicated retinal detachment of the inferior quadrants. In all patients high-density silicone oil was removed within the study period of 6 months.


The intraocular tamponade was removed after a mean period of 2 months. One third of the patients developed the clinical picture of granulomatous uveitis, which only resolved after silicone oil removal. Extraction of "heavy" silicone oil was hindered in the majority of patients due to excessive adhesion to the neuroretina, which made complete removal unsuccessful in two cases. In 2 eyes we observed emulsification with accumulation of silicone oil bubbles at the corneal endothelium and in the anterior chamber. 2 patients suffered from re-detachment after removal of the "heavý" silicone oil, which were treated with intraocular tamponade of silicone oil 5000cts.


In this study we have used a novel type of high-density silicone oil. Unfortunately, we have observed a number of side effects, such as intraocular inflammation and emulsification. Furthermore, removal was obstructed due to adhesionsof silicone oil to the retina. Additional controlled experimental and clinical studies should proceed the routine use of this newly developed silicone oil.