Artikel
High-resolution 3 Tesla Phased Array MRI in focal epilepsies: a prospective study
Hochauflösende MR Bildgebung (3Tesla) mit 8-Kanal phased-array Oberflächenspulen bei Patienten mit fokalen Epilepsien: eine prospektive Studie
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Autoren
Veröffentlicht: | 4. Mai 2005 |
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Gliederung
Text
Objective
Although detection of concordant lesions on MRI significantly improves post surgical outcomes in focal epilepsy (FE), many conventional MR studies remain negative. We evaluated the role of phased array surface coil studies performed at 3 Tesla (3T PA MRI).
Methods
46 patients were prospectively imaged with 3T PA-MRI including high matrix TSE T2, FLAIR and MPRAGE. 3T PA-MRI were reviewed by a neuroradiologist experienced in epilepsy imaging with access to clinical information. Findings were compared to reports of prior standard 1.5T MRI epilepsy studies performed at tertiary care centers.
Results
Experienced, unblinded review of 3T PA-MRI studies yielded additional diagnostic information in 54% (25/46) compared to routine clinical reads at 1.5 T. In 41% (19/46), this additional information motivated a change in clinical management. In the subgroup of patients with prior 1.5 T MRIs interpreted as normal, 3T PA-MRI resulted in the detection of a new lesion in 61% (28/46). In the subgroup of patients with known lesions, 3T PA-MRI better defined the lesion in 33%.
Conclusions
3T PA-MRI read by an experienced unblended neuroradiologist can significantly improve the presurgical evaluation of patients with FE when compared to routine clinical 1.5T studies read at tertiary care centers.