gms | German Medical Science

56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
3èmes journées françaises de Neurochirurgie (SFNC)

Deutsche Gesellschaft für Neurochirurgie e. V.
Société Française de Neurochirurgie

07. bis 11.05.2005, Strasbourg

High-resolution 3 Tesla Phased Array MRI in focal epilepsies: a prospective study

Hochauflösende MR Bildgebung (3Tesla) mit 8-Kanal phased-array Oberflächenspulen bei Patienten mit fokalen Epilepsien: eine prospektive Studie

Meeting Abstract

  • corresponding author S. Knake - MGH NMR Center, Charlestown, USA
  • C. Triantafyllou - MGH NMR Center, Charlestown, USA
  • L. L. Wald - MGH NMR Center, Charlestown, USA
  • K. Krakow - Klinik für Neurologie, Universitätsklinikum Frankfurt/Main
  • H. M. Hamer - Klinik für Neurologie, Universitätsklinikum Marburg
  • F. Rosenow - Klinik für Neurologie, Universitätsklinikum Marburg

Deutsche Gesellschaft für Neurochirurgie. Société Française de Neurochirurgie. 56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC). Strasbourg, 07.-11.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc10.05.-05.04

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dgnc2005/05dgnc0107.shtml

Published: May 4, 2005

© 2005 Knake et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Objective

Although detection of concordant lesions on MRI significantly improves post surgical outcomes in focal epilepsy (FE), many conventional MR studies remain negative. We evaluated the role of phased array surface coil studies performed at 3 Tesla (3T PA MRI).

Methods

46 patients were prospectively imaged with 3T PA-MRI including high matrix TSE T2, FLAIR and MPRAGE. 3T PA-MRI were reviewed by a neuroradiologist experienced in epilepsy imaging with access to clinical information. Findings were compared to reports of prior standard 1.5T MRI epilepsy studies performed at tertiary care centers.

Results

Experienced, unblinded review of 3T PA-MRI studies yielded additional diagnostic information in 54% (25/46) compared to routine clinical reads at 1.5 T. In 41% (19/46), this additional information motivated a change in clinical management. In the subgroup of patients with prior 1.5 T MRIs interpreted as normal, 3T PA-MRI resulted in the detection of a new lesion in 61% (28/46). In the subgroup of patients with known lesions, 3T PA-MRI better defined the lesion in 33%.

Conclusions

3T PA-MRI read by an experienced unblended neuroradiologist can significantly improve the presurgical evaluation of patients with FE when compared to routine clinical 1.5T studies read at tertiary care centers.