gms | German Medical Science

21st Annual Meeting of the German Retina Society and 8th Symposium of the International Society of Ocular Trauma (ISOT)

German Retina Society
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

Central Retinal Vein Occlusion (CRVO) without Retinal Vasculitis in Wegener's Granulomatosis

Meeting Abstract

  • Bernhard M. Stoffelns - Mainz/Germany
  • C. Kramann - Mainz/Germany
  • K. Schoepfer - Mainz/Germany

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008V131

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/rg2008/08rg132.shtml

Published: June 18, 2008

© 2008 Stoffelns et al.
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Outline

Text

Background: To describe a patient with Wegener's Granulomatosis, who developed unilateral Central Retinal Vein Occlusion (CRVO) without clinical evidence of intraocular inflammation.

Methods: A 54-year-old man developed unilateral non-ischemic CRVO associated with systemic Wegener's Granulomatosis, which had been in remission since one year. Fluorescein angiography revealed no sign of retinal vasculitis. Visual acuity was reduced to 6/10 due to diffuse macular edema. No other vascular risk factors were identified. Isovolemic hemodilution and systemic immunosuppression with prednisolon oral were initiated.

Results: After 3 months the diffuse leckage at the posterior pole was reduced, but vision dropped to 2/10 due to development of cystoid macular edema. 3 months after grid laser photocoagulation leckage was significantly reduced and vision improved to 3/10. 4 months after intravitreal injection of 10 mg triamcinolone acetonide no further leckage in the macular was detected and vision was stabilized at 5/10.

Conclusions: Wegener`s Granulomatosis should be considered in the differential diagnosis of CRVO in the young age group. In those patients intravitreal triamcinolone acetonide seems to be a good adjunct to systemic immunosuppressive therapy. Only 5 cases with isolated CRVO in Wegener´s granulomatosis have been reported in literature so far. In these patients the lack of clinical evidence of retinal vasculitis was explained by a postulated compression of the central retinal vein in a laminar or retrolaminar location by extracapillary granulomatous inflammation.Financial interests of the authors are disclosed.