Article
Measurements of neural adaptation in subjects with cochlear implants
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Authors
Published: | May 31, 2005 |
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Outline
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Introduction
Recordings of compound action potentials are increasingly used in the clinical environment as valuable tools to determine the optimal parameters of the digital speech processors.
Materials and Methods
With the Nucleus Research Platform 8 (RP8/System 4) which includes an improved Neural Response Telemetry (NRT) system, featuring higher sampling rates, longer sampling windows, an amplifier with improved linearity, saturation recovery and noise immunity, finer gain adjustments as well as new artefact cancellation/reduction methods it is also possible to determine the detailed temporal pattern when stimulating the auditory nerve with long pulse trains.
Results
Response amplitude decrease and fluctuations have been observed which are dependent on the rate of stimulation and possibly patient variables.
Conclusions
Neural adaptation effects were determined in six experimental subjects until now for rates ranging from 10 pulses per second (pps) up to 2000 pps and for pulse train durations ranging from a few milliseconds up to several seconds.