Article
Spontaneous regression of retinal angiomatous vascular changes in v.-Hippel-Lindau syndrome
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Authors
Published: | September 22, 2004 |
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Outline
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Objective
In the literature, no documentation of a spontaneous regression of angiomatous retinal lesions have been found in long-term follow-up observations. Several authors presumed a spontaneous change of big angiomas into fibrotic lesions.
Methods
A 28-year-old woman (W.) who suffered from v. Hippel-Lindau syndrome was first examined at the age of 16 years. A 15-year-old patient (N.) showed several tumors with v. Hippel-Lindau syndrome.
Results
At the age of 16 years, patient W. revealed a vascular anomaly and a circumscribed retinal edema adjacent to the optic disk. An examination nine years later showed a complete regression of the retinal vascular changes. A 15-year-old patient showed multiple small anastomosing vessels in the upper part of the left papilla, like moss fibres. At the age of 18 years a regression of these changes was found.
Conclusions
A spontaneous regression, mainly of minor angiomatous retinal lesions is possible.