gms | German Medical Science

56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
3èmes journées françaises de Neurochirurgie (SFNC)

Deutsche Gesellschaft für Neurochirurgie e. V.
Société Française de Neurochirurgie

07. bis 11.05.2005, Strasbourg

Ischemic events after endovascular treatment of unruptured aneurysms

Thrombembolische Ereignisse nach endovaskulärer Behandlung asymptomatischer Aneurysmen

Meeting Abstract

  • corresponding author I. Q. Grunwald - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • P. Papanagiotou - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • T. Struffert - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • C. Roth - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • U. Dorenbeck - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • C. Krick - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • M. Politi - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland
  • W. Reith - Department for Interventional and Diagnostic Neuroradiology, University Clinic of the Saarland

Deutsche Gesellschaft für Neurochirurgie. Société Française de Neurochirurgie. 56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC). Strasbourg, 07.-11.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc11.05.-13.10

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dgnc2005/05dgnc0248.shtml

Published: May 4, 2005

© 2005 Grunwald et al.
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Outline

Text

Objective

The purpose of this study was to evaluate the frequency and causes of thromboembolic events associated with endovascular embolization of asymptomatic aneurysms. A correlation between radiologic findings (aneurysm size, localisation, embolization time, and number of coils used, as well as patients age) was evaluated with the occurrence of thromboembolic events and clinical findings.

Methods

We evaluated 68 patients treated for unruptured intracranial aneurysms (mean age 49 years). For DWI we could include 50 aneurysms. Aneurysm size was 3 - 15 mm. Hyperintense lesions on DWI were analysed.

Results

Complete occlusion of the aneurysms was achieved in 55/68 (82%). One patient had a transient paresis. There was one infarction and one aneurysm rupture during the procedure with no consecutive neurological symptoms. We found new hyperintense lesions in 21/50 (42%). In 43% of these there was only one lesion smaller than 2mm. In 33% there was more than one lesion <2mm; in 19% we found a lesion of 2-10mm in size. In one case a lesion >10mm occurred. There was no correlation between aneurysm location and the occurrence of lesions. There was no correlation concerning the number of coils used, the size of the aneurysm, patient age and embolisation time. Mortality rate was 0%, morbidity 4.0%. If the 18 aneurysms where no DWI was obtained are included morbidity is 2.9%.

Conclusions

The high rate of thromboembolic events suggests that heparin is not sufficient to prevent ischemic lesions. Thus the use of other antiplatelet drugs, such as ASS and GPIIIb/IIa analoga should be considered.