Artikel
Blood pressure response during abpm and exercise and cardiac alterations
Blutdruck während ABDM und Ergometrie und Anpassugen des Herzens
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Autoren
Veröffentlicht: | 11. November 2004 |
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Gliederung
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Background
Some studies with a small sample size suggested that left ventricular mass index (LVMI) is more closely related to ambulatory blood pressure (ABPM) or exercise BP (ExBP) than to resting/casual BP.
Methods
In 1142 untreated patients (mean age 50.0±9.2 y., 567 males) an ABPM (SpaceLabs 90207), a bicycle exercise test (50-100watts, 5 min recovery period) and an echocardiography were performed within a 48 h period and thereafter the patients were divided into 4 groups (G1-4; [Fig. 1]) due to their BP response.
Results
Despite a normotensive daytime BP during ABPM, patients of G2 with an increased ExBP (ExBP+, >200/>100 mmHg at 100 watts) revealed significantly (p<0.05 - p<0.001) higher values for LVMI, wall thickness (IVS, PWT) left ventricular enddiastolic dimension (LVID), left atrial size (LA) and a disturbed diastolic function (E/A<1) compared to G1 (normal ExBP, ExBP-) and comparable values to G3 (daytime ABPM hypertensive >135/85, EXBP-).
Conclusions
These data suggest that exercise BP may be an important determinant for cardiac alterations even in patients with a normotensive response during ABPM.