Artikel
OCT: Future perspectives?
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Veröffentlicht: | 22. September 2004 |
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Recent development of ultrabroad bandwidth light sources has recently enabled significant improvement of ophthalmic axial OCT imaging resolution, demonstrating the potential of ultrahigh resolution OCT (UHR OCT) to perform non-invasive optical biopsy, i.e. the in vivo visualization of microstructural morphology in situ, which had previously only been possible with histopathology. Therefore UHR OCT allows detection of intraretinal changes that can be used for diagnosis of retinal disease in its early stages, when treatment is most effective and irreversible damage can be prevented or delayed. Furthermore it may provide a better understanding of the pathogenesis of several macular pathologies as well as the development of new therapy approaches. Future developments of ophthalmic OCT include high speed, three dimensional retinal imaging, combining adaptive optics and UHR OCT, spatially resolved spectroscopic OCT, functional imaging as well as OCT imaging with enhanced penetration into the choroid by employing novel wavelength regions.