gms | German Medical Science

International Conference on SARS - one year after the (first) outbreak

08. - 11.05.2004, Lübeck

Civets are susceptible to infection by SARS coronavirus

Talk

  • author presenting/speaker Donglai Wu - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Changchun Tu - Changchun University of Agriculture and Animal Sciences, Changchun, China
  • Chaoan Xin - College of Veterinary Medicine, South China Agriculture University, Guangzhou, China
  • Hua Xuan - Changchun University of Agriculture and Animal Sciences, Changchun, China
  • Qingwen Meng - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Yonggang Liu - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Yedong Yu - Guangdong Provincial Veterinary Station of Epidemic Prevention and Supervision, Guangzhou, China
  • Yuantao Guan - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Yu Jiang - Changchun University of Agriculture and Animal Sciences, Changchun, China
  • Xunnan Yin - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Linfa Wang - CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Australia
  • Muping Wang - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Changwen Li - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Shengwang Liu - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Ming Liao - College of Veterinary Medicine, South China Agriculture University, Guangzhou, China
  • Li Feng - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Hua Xiang - Changchun University of Agriculture and Animal Sciences, Changchun, China
  • Jinfu Sun - Changchun University of Agriculture and Animal Sciences, Changchun 130062, China
  • Jinding Chen - College of Veterinary Medicine, South China Agriculture University, Guangzhou 510246, China
  • Yanwei Sun - Guangdong Provincial Veterinary Station of Epidemic Prevention and Supervision, Guangzhou, China
  • Shoulin Gu - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Nihong Liu - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Dexia Fu - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China
  • Gary Crameri - CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Australia
  • Bryan T. Eaton - CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Australia
  • corresponding author Xiangang Kong - National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, Harbin, China

International Conference on SARS - one year after the (first) outbreak. Lübeck, 08.-11.05.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04sars10.02

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/sars2004/04sars052.shtml

Published: May 26, 2004

© 2004 Wu et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Severe acute respiratory syndrome (SARS) was first recognized in Guangdong and caused by a novel virus now known as SARS coronavirus (SARS-CoV). Epidemiological data strongly suggest an animal origin for SARS-CoV although the reservoir host is yet to be identified. The discovery of SARS-CoV-like viruses in masked palm civets and the relationship of their genomic sequences with viruses isolated from humans raise the possibility that civets may play a key role in SARS-CoV transmission. Here we show that civets are susceptible to experimental infection with SARS-CoV and display clinical signs during the early stage of infection.