Article
Radiotherapy of large uveal melanoma
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Published: | June 29, 2009 |
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Outline
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Although brachytherapy represents without doubt the gold standard for the therapy of small to medium size uveal melanoma, guidelines for the treatment of large and highly prominent tumours do not exist. Moreover Proton Therapy and Gamma Knife radiosurgery are quite upfront about treated cases and follow-up available. Recently there is a rising number of reports about treatment of large uveal melanoma with isocentric as well as non isocentric – robotized linear accelerators.Gathering information from more than 170 cases treated with Gamma Knife radiosurgery the problems of radiotherapy for the eye and ist clinical solutions should be presented. The demands for a highly refined instrument of radiation therapy for the eye is defined. Comparison between “single fraction” versus “fractionated radiotherapy” is presented.