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14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT)

17.06. - 21.06.2019, Berlin

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Biological therapy in delayed distal radius fracture healing. Case report

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  • presenting/speaker Adriana Pemoff - Hospital Fernandez, Fundación Las Manos del Músico, Climba, Buenos Aires, Argentina
  • Candelaria Torre - Hospital Fernandez, Fundación Las Manos del Músico, Buenos Aires, Argentina
  • Hernán Blanchetiere - Hospital Fernandez, Fundación Las Manos del Músico, Climba, Buenos Aires, Argentina
  • Soledad Lett - Hospital Fernandez, Fundación Las Manos del Músico, Buenos Aires, Argentina
  • Gabriel Clembosky - Climba, Buenos Aires, Argentina
  • Maria Eulalia Landro - Hospital Fernandez, Buenos Aires, Argentina

International Federation of Societies for Surgery of the Hand. International Federation of Societies for Hand Therapy. 14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT). Berlin, 17.-21.06.2019. Düsseldorf: German Medical Science GMS Publishing House; 2020. DocIFSSH19-1104

doi: 10.3205/19ifssh0182, urn:nbn:de:0183-19ifssh01822

Published: February 6, 2020

© 2020 Pemoff et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

Outline

Text

Objectives/Interrogation: Currently, the study of cellular and molecular biology has allowed to restore or improve organs and tissues function injured by certain diseases or traumatisms.

Recent studies indicate that bone marrow concentrate with its mesenchymal and hematopoietic stem cells population, along with growth factors, shows anti-inflammatory, immunomodulatory, chondrogenic, osteogenic and osteoinductive qualities.

Platelet-rich plasma is a derivative of autologous peripheral blood, a concentration of platelets in a small amount of plasma, which has a very important role in inflammatory modulation and specially in regulation and stimulation of regenerative processes of different tissues. The aim of our study is to demonstrate the effectiveness of this type of biological therapy in delayed fracture healing, presenting a clinical case.

Methods: A 41-year-old patient who works as a legal assistant, suffered a motorcycle accident and presented a distal radius fracture of his right wrist, treated with open reduction and internal fixation with distal radius blocked plate. He arrives to our medical control after 7 months without radiographic or tomographic consolidation signs, mild pain during forced pronation or supination. With diagnosis of delayed fracture healing, we offered the biological therapy contribution: percutaneous application of bone marrow concentrate (from his iliac crest) + peripheral blood PRP.

Results and Conclusions: After the serial radiological and tomographic controls, changes in the consolidation process began to be seen at the 6th week and was completed after 6 months of the biological therapy, without pain in the fracture focus and complete mobility of the wrist.

We conclude that percutaneous application of autologous biological supply: bone marrow concentrate + platelet-rich plasma is a minimally invasive, effective, safe, economical and viable technique for the treatment of delayed fracture healing.