gms | German Medical Science

14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT)

17.06. - 21.06.2019, Berlin

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Injection of a concentrated bone marrow punctate into denervated muscles can improve the results of their reinnervation. Our first clinical experience

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  • presenting/speaker Igor Kurinniy - SI ITO of NAMS of Ukraine, Kyiv, Ukraine
  • Serhii Strafun - SI ITO of NAMS of Ukraine, Kyiv, Ukraine
  • Andrii Lysak - SI ITO of NAMS of Ukraine, Kyiv, Ukraine

International Federation of Societies for Surgery of the Hand. International Federation of Societies for Hand Therapy. 14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT). Berlin, 17.-21.06.2019. Düsseldorf: German Medical Science GMS Publishing House; 2020. DocIFSSH19-1090

doi: 10.3205/19ifssh0181, urn:nbn:de:0183-19ifssh01816

Published: February 6, 2020

© 2020 Kurinniy et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

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Objectives/Interrogation: Determine the effectiveness of concentrated punctate bone marrow injection into muscle after their denervation.

Methods: During 2016-2018, to 56 patients (35 men, 21 women) with peripheral nerves injury (brachial plexus - 43; axillary nerve - 3; radial nerve - 6; median nerve - 3; ulnar nerve - 1) concentrated bone marrow punctate injection into the denevated muscle was performed after nerve surgery. Scheme: 1 week prior to surgery - PRP injection, during surgery - injection of a concentrated bone marrow punctate into the target muscle, and then PRP injection in 2 weeks postop. Subsequently, injection of concentrated bone marrow punctate was repeated 1 time every three months until the moment of effective reinvention. The control of hypotrophy and reinnervation of the muscle was performed using sonography and ENMG.

Results and Conclusions: Control sonographic examinations have shown that the injection of a concentrated bone marrow punctate into the denervated muscle significantly slows the process of hypotrophy. In the ENMG of target muscles - large motor units was detected (which significantly exceeded those that could be recorded in the muscles which did not administer the injection of a concentrated bone marrow punctate). According to the authors, this suggests the stimulation of terminal collateral sprauting.

Injection of concentrated bone marrow punctate into the denervated muscles - signifycantly improves the process of their reinnervation due to the slowdown of hypotrophy, and stimulation of terminal collateral sprauting.