gms | German Medical Science

14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT)

17.06. - 21.06.2019, Berlin

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Ossification of a Dupuytren’s Cord Following Xiapex (collagenase clostridium histolyticum) Injection. A Case Report

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  • presenting/speaker Robin McManus - Blackrock Clinic, Dublin, United Kingdom
  • Kevin McGarry - Department of Plastic Surgery, Ulster Hospital, Belfast, United Kingdom
  • Phil Grieve - Blackrock Clinic, Dublin, United Kingdom

International Federation of Societies for Surgery of the Hand. International Federation of Societies for Hand Therapy. 14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT). Berlin, 17.-21.06.2019. Düsseldorf: German Medical Science GMS Publishing House; 2020. DocIFSSH19-215

doi: 10.3205/19ifssh0066, urn:nbn:de:0183-19ifssh00665

Published: February 6, 2020

© 2020 McManus et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

Outline

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Objectives/Interrogation: In this case we present a previously unpublished outcome in Dupuytren's disease following collagenese treatment - ossification of the Dupuytren's cord, complicating secondary redo surgery.

Methods: A 67 year old right hand dominant male presented to the hand clinic with a seven year history of Dupuytren's contracture affecting his left index, middle and ring fingers. For primary management he was offered collagenese injection to the little finger. Despite initial improvement he had an early relapse prompting formal dermofasciectomy. Intraoperatively an ossified cord was identified complicating the resection process.

Results and Conclusions: To our knowledge this is the first reported case of Dupuytren's cord ossification following collagenese injection. On literature review no causal link was identified between the treatment and the pathology. However given the increasing use of collagenese in primary Dupuytren's management it is possible further cases may present.