gms | German Medical Science

27. Wissenschaftlicher Kongress der Deutschen Hochdruckliga

Deutsche Liga zur Bekämpfung des hohen Blutdrucks – Deutsche Hypertonie Gesellschaft e. V.

26. bis 29.11.2003, Bonn

Prevalence of increasing carotid artery atherosclerosis in chronic renal failure: an ultrasonographic study

Meeting Abstract (Hypertonie 2003)

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  • presenting/speaker G.L. Kissinger - Krankenhaus der Barmherzigen Brüder, Salzburg, Austria
  • F. Hoppichler - Krankenhaus der Barmherzigen Brüder, Salzburg, Austria

Hypertonie 2003. 27. Wissenschaftlicher Kongress der Deutschen Hochdruckliga. Bonn, 26.-29.11.2003. Düsseldorf, Köln: German Medical Science; 2004. Doc03hochP4

The electronic version of this article is the complete one and can be found online at:

Published: November 11, 2004

© 2004 Kissinger et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



To evaluate the prevalence of carotid artery atherosclerosis in patients with chronic renal failure compared to patients with ischemic heart disease (IHD) and to patients without renal failure.

We studied 115 patients with chronic renal disease (creatinine > 2 mg/dl) without known cardio-vascular disease and without diabetes by using high-resolution B-mode ultrasound, compared to 105 patients with IHD and 65 patients without renal failure. Carotid atherosclerosis was classified as: normal, thickened intima-media, non-stenotic plaque and stenotic plaque.

Compared with subjects without renal disease, the frequency of patients with renal failure without known IHD increased significantly from normal to stenotic plaque. No difference was found comparing patients with renal diasease and with subjects with IHD (p=0,57). Patients with renal disease and non renal disease subjects with IHD showed a similiar association of the increasing degree of carotid atherosclerosis. But significantly stronger compared with patients without diabetes or IHD (p<0,02).

Patients with renal failure without known IHD show an advanced degree of carotid atherosclerosis damage similiar to patients without renal disease with IHD and significantly higher with patients without renal failure. Our data support an aggressive and early prevention of cardiovascular disease in patients with renal failure.